ID   A0A2K8KFN2_9MOLU        Unreviewed;       443 AA.
AC   A0A2K8KFN2;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Leucyl aminopeptidase {ECO:0000313|EMBL:ATX70503.1};
GN   Name=pepA {ECO:0000313|EMBL:ATX70503.1};
GN   ORFNames=SCLAR_v1c01720 {ECO:0000313|EMBL:ATX70503.1};
OS   Spiroplasma clarkii.
OC   Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC   Spiroplasma.
OX   NCBI_TaxID=2139 {ECO:0000313|EMBL:ATX70503.1, ECO:0000313|Proteomes:UP000231179};
RN   [1] {ECO:0000313|EMBL:ATX70503.1, ECO:0000313|Proteomes:UP000231179}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CN-5 {ECO:0000313|EMBL:ATX70503.1,
RC   ECO:0000313|Proteomes:UP000231179};
RA   Tsai Y.-M., Chang A., Lo W.-S., Kuo C.-H.;
RT   "Complete genome sequence of Spiroplasma clarkii CN-5 (DSM 19994).";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M17 family.
CC       {ECO:0000256|ARBA:ARBA00009528}.
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DR   EMBL; CP024870; ATX70503.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K8KFN2; -.
DR   Proteomes; UP000231179; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0030145; F:manganese ion binding; IEA:InterPro.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00433; Peptidase_M17; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR011356; Leucine_aapep/pepB.
DR   InterPro; IPR000819; Peptidase_M17_C.
DR   PANTHER; PTHR11963; LEUCINE AMINOPEPTIDASE-RELATED; 1.
DR   PANTHER; PTHR11963:SF23; ZGC:152830; 1.
DR   Pfam; PF00883; Peptidase_M17; 1.
DR   PRINTS; PR00481; LAMNOPPTDASE.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00631; CYTOSOL_AP; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438,
KW   ECO:0000313|EMBL:ATX70503.1}; Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000231179}.
FT   DOMAIN          299..306
FT                   /note="Cytosol aminopeptidase"
FT                   /evidence="ECO:0000259|PROSITE:PS00631"
SQ   SEQUENCE   443 AA;  48929 MW;  1EFE9959412FF3DE CRC64;
     MITKNLKTNF LKLSAYKKNT KSSLFIQKTG QTTLVDTEKT LYICLTEATT IRKIQTIIKK
     FVKQNKYDLN IDLDSFVEVF QNNIDLMQAV IETLMYQNHP VLSMKTTQKT EPSFNFLVSE
     TWASLFSELA LKTEFSNFAR DLQNLPPNIA TSIKLAELIE QKANEVGGIK TTILNKTEIQ
     NLKMELLLAV NAGSKIEPRV VVLEYVGDPK APKVALVGKG ITFDSGGYNL KSSPYIKDMK
     FDMTGTAVVC GAVMALAKAK AKCNVVAIAV LTDNRIGETA MLPEAIYQSM KGLTVEITNT
     DAEGRLVLAD GITYALQEQK AQKIITAATL TGAIRIALGR WFVGMFSNND KFCEEFSTAS
     QKAQEYCWRL PLLEEHLDVM KRSKIADLVN SEPGAEAGSS TAAAFLQAFV EDKPFIHVDL
     SGVGRLESEG TAPMLKTIFE LLK
//