ID   A0A2K8KHQ6_9MOLU        Unreviewed;       436 AA.
AC   A0A2K8KHQ6;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=DNA mismatch repair protein MutH {ECO:0000313|EMBL:ATX71223.1};
GN   Name=mutH {ECO:0000313|EMBL:ATX71223.1};
GN   ORFNames=SCLAR_v1c09170 {ECO:0000313|EMBL:ATX71223.1};
OS   Spiroplasma clarkii.
OC   Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales; Spiroplasmataceae;
OC   Spiroplasma.
OX   NCBI_TaxID=2139 {ECO:0000313|EMBL:ATX71223.1, ECO:0000313|Proteomes:UP000231179};
RN   [1] {ECO:0000313|EMBL:ATX71223.1, ECO:0000313|Proteomes:UP000231179}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CN-5 {ECO:0000313|EMBL:ATX71223.1,
RC   ECO:0000313|Proteomes:UP000231179};
RA   Tsai Y.-M., Chang A., Lo W.-S., Kuo C.-H.;
RT   "Complete genome sequence of Spiroplasma clarkii CN-5 (DSM 19994).";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP024870; ATX71223.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K8KHQ6; -.
DR   REBASE; 225842; SclCN5CORF9140P.
DR   Proteomes; UP000231179; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR   CDD; cd22356; Sau3AI_N-like; 1.
DR   Gene3D; 3.40.600.10; DNA mismatch repair MutH/Restriction endonuclease, type II; 2.
DR   InterPro; IPR011337; DNA_rep_MutH/RE_typeII_Sau3AI.
DR   InterPro; IPR037057; DNA_rep_MutH/T2_RE_sf.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   Pfam; PF02976; MutH; 1.
DR   SMART; SM00927; MutH; 1.
DR   SUPFAM; SSF52980; Restriction endonuclease-like; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000231179}.
FT   DOMAIN          48..144
FT                   /note="DNA mismatch repair MutH/Type II restriction enzyme
FT                   Sau3AI"
FT                   /evidence="ECO:0000259|SMART:SM00927"
FT   REGION          174..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        174..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   436 AA;  51172 MW;  F58B7A8BC6A367AA CRC64;
     MKEIYDLAKS AIGKSIREII GDNVDELIIN DKNKGTVGNL IQKYLFKIEP NNISEADFKE
     LGLDLELKVI PLLERSLKNK LAPKERMVLG MINYHKIVDE TFEESSFLKK NRHLLIMTYL
     YDYNADKLDY KIIDAFLYDV TADDFFPDIK SDWEKINKAV VSGEAHLLTE KNNNILSPST
     KGGSENNRKQ PNSDEIAKGR AYSYKVSFVK KIIENFAQEE FDFFIKNLNK INYIEKEDIE
     AEIYDFLNSL IGTKIPKGDK IEKNWHENVF KKTVREKDEK MFQKMYKNPY LKFSHKVLDE
     KGNLQEEINT NVDILPLEII NEEFENSSLF NNVIDKKYVI IGIDKKTNIF KKYWTFTFND
     SQIEKCKIAF EKVKERIQNY FNSKSDEKFT FNLKKSDDLA IHLRPHAKNG SKTYEKKGVP
     LDIVIHEWWI NKKEIT
//