ID A0A2K8KJI2_9RHOB Unreviewed; 302 AA.
AC A0A2K8KJI2;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=S-adenosylmethionine uptake transporter {ECO:0000256|ARBA:ARBA00019341};
GN ORFNames=BG454_15845 {ECO:0000313|EMBL:ATX67108.1};
OS Rhodobaca barguzinensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodobaca.
OX NCBI_TaxID=441209 {ECO:0000313|EMBL:ATX67108.1, ECO:0000313|Proteomes:UP000228948};
RN [1] {ECO:0000313|EMBL:ATX67108.1, ECO:0000313|Proteomes:UP000228948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=alga05 {ECO:0000313|Proteomes:UP000228948};
RA Kopejtka K., Tomasch J.M., Bunk B., Koblizek M.;
RT "Revised Sequence and Annotation of the Rhodobaca barguzinensis strain
RT alga05 Genome.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transports S-adenosylmethionine.
CC {ECO:0000256|ARBA:ARBA00004028}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003942};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU003942}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
CC {ECO:0000256|ARBA:ARBA00009853}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
CC {ECO:0000256|RuleBase:RU003942}.
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DR EMBL; CP024899; ATX67108.1; -; Genomic_DNA.
DR RefSeq; WP_071481552.1; NZ_SODJ01000001.1.
DR AlphaFoldDB; A0A2K8KJI2; -.
DR STRING; 441209.GCA_001870665_02950; -.
DR KEGG; rbg:BG454_15845; -.
DR OrthoDB; 9783707at2; -.
DR Proteomes; UP000228948; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3730.20; -; 2.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR045324; Small_multidrug_res.
DR PANTHER; PTHR22911; ACYL-MALONYL CONDENSING ENZYME-RELATED; 1.
DR PANTHER; PTHR22911:SF6; RH69884P; 1.
DR Pfam; PF00892; EamA; 1.
DR Pfam; PF00893; Multi_Drug_Res; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000228948};
KW Transmembrane {ECO:0000256|RuleBase:RU003942, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022970}.
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 128..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 162..296
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 302 AA; 32492 MW; A532B10401863F61 CRC64;
MNEWLLSLVG TPEGARLATF LALTAALAHA VFGALQKGGH DPWLSRGSID LSLVVLSAPI
ALFVFGLPDP HMWPVLVGVV VIHFIYKMAM ALAYEKAAFT VVYPVVRGTG PLITVIAAML
FFGEQYTALQ WLGVACLSGG ILLLALRNLS EEQIDLRALK VGLVWALAGG VMVAVYTTYD
AWAIRLSGDP LGFLAWFFFL SSVDFMILGA LRYRNMAQPP RPLPLLLRGL AGALIAYISF
GAVMIATLIG KVGEAAVLRE TSTVFAAFIG WFILKERVGP RKLALMCLIA LGAVIMELGR
AS
//
