ID A0A2K8L8U6_9PROT Unreviewed; 923 AA.
AC A0A2K8L8U6;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Sodium/potassium-transporting ATPase subunit alpha {ECO:0000313|EMBL:ATX82311.1};
DE EC=3.6.3.9 {ECO:0000313|EMBL:ATX82311.1};
GN ORFNames=Ga0123462_1448 {ECO:0000313|EMBL:ATX82311.1};
OS Mariprofundus ferrinatatus.
OC Bacteria; Pseudomonadota; Zetaproteobacteria; Mariprofundales;
OC Mariprofundaceae; Mariprofundus.
OX NCBI_TaxID=1921087 {ECO:0000313|EMBL:ATX82311.1, ECO:0000313|Proteomes:UP000231637};
RN [1] {ECO:0000313|EMBL:ATX82311.1, ECO:0000313|Proteomes:UP000231637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CP-8 {ECO:0000313|EMBL:ATX82311.1,
RC ECO:0000313|Proteomes:UP000231637};
RA McAllister S.M., Kato S., Chan C.S., Chiu B.K., Field E.K.;
RT "Isolation and genomic insights into novel planktonic Zetaproteobacteria
RT from stratified waters of the Chesapeake Bay.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP018800; ATX82311.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8L8U6; -.
DR KEGG; mfn:Ga0123462_1448; -.
DR OrthoDB; 9807843at2; -.
DR Proteomes; UP000231637; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0015662; F:P-type ion transporter activity; IEA:UniProt.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR006068; ATPase_P-typ_cation-transptr_C.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43294:SF22; P-TYPE ATPASE; 1.
DR PANTHER; PTHR43294; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA; 1.
DR Pfam; PF13246; Cation_ATPase; 1.
DR Pfam; PF00689; Cation_ATPase_C; 1.
DR Pfam; PF00690; Cation_ATPase_N; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF08282; Hydrolase_3; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00121; NAKATPASE.
DR SFLD; SFLDG00002; C1.7:_P-type_atpase_like; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:ATX82311.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000231637};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 67..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 716..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 781..806
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 818..838
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 858..879
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 891..909
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..96
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
SQ SEQUENCE 923 AA; 101979 MW; E41E827E5267557C CRC64;
MTDIENPMVE ACRAEVPPEL LKRIHQVPTD EVLEQLSTSE QGLENAEVRA RRKCYGINRL
SEKKEMLIVL QFLLQFHNLF SYLLLAGAAL SFLSEYLVPG EGSFYIAWAL LGVTLLNAIF
TFFQEQKAKK AMKAFRNLMT SQAVVLRGGE RIQIESEHLV PGDIIVLAEG DRITADARLI
EQSMLKVDHS ALTGESEPQL RSLNATSGNV LRSRNMVFSG TLVQSGTGTA VVVATGDHTQ
IGKIARETSE VEQVESHLQR QIAHFIRIIS YIAISLGISF FLLDYLIARN PIWIDLVFAI
GIIVANVPEG LLPTVTLTLS LAAQRMARLN VLVKNIDAIE TLGSLTVICS DKTGTLTENN
LNVHAICMND LCYDFDRSQG RLLLEQKHVH LRNIPGMQDF NDILVLCNNS TVSREKSFGD
ATELSLKSFV SAFSNISYIA ENQPRLHEIP FSSESRFMVT VNSYNTNARA YLKGASEVVL
EMCTHYFENG RCSELTDEVR KKLLEWDVSY AGQGFRVLGC AIKEVEDEHG DLEGGFCFYG
LVVMQDPPRP EVAESVRLCK EAGIRVIVIS GDQESTVEHI ARQTGIIEGD SAVVVNGADL
PELSDERLKE LLQSPELLFA RTLPRDKLRI VTLLKEMGEV VAVTGDGVND APALRRADVG
IAMGRSGTEV AKEAADIVLL DDNFTSIVSA IKAGRAAYDN IKSFITYILT SNTPEIVPFL
LFILLGWPLA LPVLLILAID LGTDMIPAIG LGVEKPESDI MQRPPRDPSA RLLTWRMIAR
SYGFIGPLQT AFSYIIFFDI LFAGGWSWGR ELAVNDPLYM QAITGFFATI IITQMFNVFA
CRTTKLSAFS KGLFSNRLIL AGIGSELLLL VVIALTPVGQ TIFGTAAFDP GYLPLMLLFG
AVILLCEELR KYLYRTRGIF GLE
//
