ID A0A2K8LAL3_9PROT Unreviewed; 306 AA.
AC A0A2K8LAL3;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=6-phosphogluconate dehydrogenase (Decarboxylating) {ECO:0000313|EMBL:ATX81296.1};
DE EC=1.1.1.343 {ECO:0000313|EMBL:ATX81296.1};
DE EC=1.1.1.44 {ECO:0000313|EMBL:ATX81296.1};
GN ORFNames=Ga0123462_0421 {ECO:0000313|EMBL:ATX81296.1};
OS Mariprofundus ferrinatatus.
OC Bacteria; Pseudomonadota; Zetaproteobacteria; Mariprofundales;
OC Mariprofundaceae; Mariprofundus.
OX NCBI_TaxID=1921087 {ECO:0000313|EMBL:ATX81296.1, ECO:0000313|Proteomes:UP000231637};
RN [1] {ECO:0000313|EMBL:ATX81296.1, ECO:0000313|Proteomes:UP000231637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CP-8 {ECO:0000313|EMBL:ATX81296.1,
RC ECO:0000313|Proteomes:UP000231637};
RA McAllister S.M., Kato S., Chan C.S., Chiu B.K., Field E.K.;
RT "Isolation and genomic insights into novel planktonic Zetaproteobacteria
RT from stratified waters of the Chesapeake Bay.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC {ECO:0000256|ARBA:ARBA00004959}.
CC -!- SIMILARITY: Belongs to the 6-phosphogluconate dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008419}.
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DR EMBL; CP018800; ATX81296.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8LAL3; -.
DR KEGG; mfn:Ga0123462_0421; -.
DR OrthoDB; 9804542at2; -.
DR UniPathway; UPA00115; -.
DR Proteomes; UP000231637; Chromosome.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:UniProtKB-EC.
DR GO; GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR004849; 6DGDH_YqeC.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006114; 6PGDH_C.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006183; Pgluconate_DH.
DR NCBIfam; TIGR00872; gnd_rel; 1.
DR PANTHER; PTHR11811; 6-PHOSPHOGLUCONATE DEHYDROGENASE; 1.
DR PANTHER; PTHR11811:SF67; 6-PHOSPHOGLUCONATE DEHYDROGENASE YQEC-RELATED; 1.
DR Pfam; PF00393; 6PGD; 1.
DR Pfam; PF03446; NAD_binding_2; 1.
DR PRINTS; PR00076; 6PGDHDRGNASE.
DR SMART; SM01350; 6PGD; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Gluconate utilization {ECO:0000256|ARBA:ARBA00023064};
KW Oxidoreductase {ECO:0000313|EMBL:ATX81296.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000231637}.
FT DOMAIN 171..299
FT /note="6-phosphogluconate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01350"
SQ SEQUENCE 306 AA; 32609 MW; 2C23E28F7BD6D60A CRC64;
MQLAMVGMGR MGGNMARRLA LGGHRVVAFD VDFETTKAIA AEHHEIHPVA DLAALVAAMP
APRAIWIMVP HQVVDATIAA LLDAGLESGD LIIDGGNSNY REGQHRACKL AESDIHFADC
GTSGGIWGLK NGYSLMIGGK SEAIELIAPA LTTLAANDGK GWAHVGPVGS GHFVKMVHNG
IEYGMMQAFA EGFELMQAKS EFALDMHQIA RVWQKGSVVS SWLLDLTADA LEQDKGLSSL
SDYMDDSGEG RWTVNESVDL GVPTPVLTLA LQMRFRSRQQ DAYSGKIVNA MRAGFGGHAI
KPAGKA
//
