ID A0A2K8NY28_9MOLU Unreviewed; 899 AA.
AC A0A2K8NY28;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=PTS system, beta-glucoside-specific IIABC component {ECO:0000313|EMBL:ATZ18732.1};
GN Name=bglF {ECO:0000313|EMBL:ATZ18732.1};
GN ORFNames=ESOMN_v1c03500 {ECO:0000313|EMBL:ATZ18732.1};
OS Williamsoniiplasma somnilux.
OC Bacteria; Mycoplasmatota; Mollicutes; Entomoplasmatales;
OC Williamsoniiplasma.
OX NCBI_TaxID=215578 {ECO:0000313|EMBL:ATZ18732.1, ECO:0000313|Proteomes:UP000232230};
RN [1] {ECO:0000313|EMBL:ATZ18732.1, ECO:0000313|Proteomes:UP000232230}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PYAN-1 {ECO:0000313|EMBL:ATZ18732.1,
RC ECO:0000313|Proteomes:UP000232230};
RA Lo W.-S., Gasparich G.E., Kuo C.-H.;
RT "Genome sequence of Entomoplasma somnilux PYAN-1 (ATCC 49194).";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP024965; ATZ18732.1; -; Genomic_DNA.
DR RefSeq; WP_024863255.1; NZ_CP024965.1.
DR AlphaFoldDB; A0A2K8NY28; -.
DR KEGG; esx:ESOMN_v1c03500; -.
DR Proteomes; UP000232230; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR011055; Dup_hybrid_motif.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR001127; PTS_EIIA_1_perm.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR NCBIfam; TIGR00830; PTBA; 1.
DR PANTHER; PTHR30175; PHOSPHOTRANSFERASE SYSTEM TRANSPORT PROTEIN; 1.
DR PANTHER; PTHR30175:SF3; PTS SYSTEM N-ACETYLMURAMIC ACID-SPECIFIC EIIBC COMPONENT; 1.
DR Pfam; PF00358; PTS_EIIA_1; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF51261; Duplicated hybrid motif; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51093; PTS_EIIA_TYPE_1; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS01035; PTS_EIIB_TYPE_1_CYS; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Reference proteome {ECO:0000313|Proteomes:UP000232230};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 287..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..568
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..624
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..131
FT /note="PTS EIIA type-1"
FT /evidence="ECO:0000259|PROSITE:PS51093"
FT DOMAIN 189..271
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT DOMAIN 289..694
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT COILED 730..760
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 211
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 899 AA; 101134 MW; 90438BC98333FDDE CRC64;
MSVPPQKINI FAPCDGEIKK LKDLNDGVFS KGMLGNGFFI IPKNNEFYTP LEDAKISLIT
DTKHAYFFEL ENNINLLMHI GIDTVKLNGI PFKEHVSINQ KVNLNTKIVD VDLEYIKSMG
LQTQVPITLD VDTKNSKYIF KFNKKGNVKR GELIGYFELK EDKKNPNKFL NNKNNIDFED
YFNQKDFYTK LALKINELVG LKNNYNDVYN CMTRLRFKIK NKNLVQEKQI RQIEGVKGII
WNNNELQIVI GQDVYKVKDA IISFNNGINL QDFTLKNNQK ENLVKKFFSI ISGIMVPLIP
LLIGAGLMMG IVSILQISNL MPKIVYTIPD GQLLPTNTYF IQDVNVFWGI LKVTSDVPLK
FLALFTAISA SKYFNFNPLL GAGIGLIISN PILFYGSGFG DKGIQWDLIT TNVNPDPTTN
PAWFGFSKIP IMIFANRPFV AMLSIFVASK LDVWIKGWIH PSLELVFRPF VVLLTIALLT
FFVIGPIYYI IETIIAGLMY YLTLAPFGIA QAILSLFWPI LVVFGIHLPV STLIQVQSFA
QGQVSALLPA AAMTQWGSVG ALLGLLIISK NSKTKNEAIG ALPPGIMGIT EPAIYGVTLP
RFKPFVAACL GGAIGGLFIG AMGVSSRVSS GLGVFGFIGY FSDPVDPSSA PTNLLPNIQN
GLFFILASLI ACASSIVFTS LLHVERIKET SLIQKINNNI VKFVKLSSIF SEETFNKFKS
EIKAISFNVS KEEKKEIKKL EKQILKNANL KELYNSLLKK DKKIKNLLLK KGQKAVKNND
TLKVEKIYEK HITDIYGNKK RQLQEQIKLE NEKINFDLLK TLVAKNKNTI LENIQKIDKE
FNTNILKYQN EYLNALNSLL IFYNEAQPIE IEQSILNDFN DLKLNLQTNG KKEKTRKAI
//
