ID   A0A2K8P6Z7_STRLA        Unreviewed;       530 AA.
AC   A0A2K8P6Z7;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Carboxylesterase A {ECO:0000313|EMBL:ATZ22522.1};
DE            EC=3.1.1.- {ECO:0000313|EMBL:ATZ22522.1};
GN   Name=caeA3 {ECO:0000313|EMBL:ATZ22522.1};
GN   ORFNames=SLAV_03055 {ECO:0000313|EMBL:ATZ22522.1}, SLLC_01090
GN   {ECO:0000313|EMBL:QUQ52366.1};
OS   Streptomyces lavendulae subsp. lavendulae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ22522.1, ECO:0000313|Proteomes:UP000231791};
RN   [1] {ECO:0000313|EMBL:ATZ22522.1, ECO:0000313|Proteomes:UP000231791}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ22522.1,
RC   ECO:0000313|Proteomes:UP000231791};
RA   Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA   Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA   Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT   "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT   3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT   angucycline-type antibiotic auricin.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:QUQ52366.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Del-LP {ECO:0000313|EMBL:QUQ52366.1};
RA   Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA   Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA   Kalinowski J., Kormanec J.;
RT   "The linear plasmid pSA3239 is essential for the replication of the
RT   Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL   Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S33 family.
CC       {ECO:0000256|ARBA:ARBA00010088}.
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DR   EMBL; CP024985; ATZ22522.1; -; Genomic_DNA.
DR   EMBL; CP073778; QUQ52366.1; -; Genomic_DNA.
DR   RefSeq; WP_063760281.1; NZ_JOEW01000010.1.
DR   AlphaFoldDB; A0A2K8P6Z7; -.
DR   GeneID; 82162689; -.
DR   KEGG; slx:SLAV_03055; -.
DR   OrthoDB; 9796770at2; -.
DR   Proteomes; UP000231791; Chromosome.
DR   Proteomes; UP000676025; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR013595; Pept_S33_TAP-like_C.
DR   PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR   PANTHER; PTHR43248:SF29; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF08386; Abhydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ATZ22522.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000231791}.
FT   DOMAIN          115..272
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   DOMAIN          429..515
FT                   /note="Peptidase S33 tripeptidyl aminopeptidase-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08386"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   530 AA;  55392 MW;  3086D68771426281 CRC64;
     MAHHRISPRG TPPKRLKDPH STVSTAVNTV AVAALVLLAG AGGATPAGAT SRAAAPAARF
     VPGPCPATPE AVAALDGAKC GFLEVPENRS RPSARTIRLA VAVIPAASPK PAQDPIVYMA
     GGPGGDAFDD ISLLVDAGVN RDRDLIVMAQ RGNLHSQPNL ACPEIDRASA RAVGLRYDDP
     SARRLLVGAA KQCRDRLAAD GTDLGAYNTG ENAADFADLR TALGVRQWNV YSYSYGSDLA
     LTYLREHPRG IRSVALDSVT PPQAVNLPWT WSSAREGVDA VLGACRAEPR CQGRYPDVAR
     TLTEQVRKLE AHPLTLHAAP PSGGKPVKVV LDGGALVNLI VGNGVRPADL PAALDELARG
     NPQRFARARA ADAYPAVGRT AHGLTESVAC GEWAPGYTQS QVLDAGREAF PGMPDTVLAQ
     APQLPFQREV CRVWNVPDRT AAQRVATVSA VPALVLSGTF DTKTGASWGA RTARDLSRST
     AVRIPGVGHF VVPQSPCAQT VLASFFARPT APDTGCVAGL APKPFTIAPK
//