ID A0A2K8P722_STRLA Unreviewed; 678 AA.
AC A0A2K8P722;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Bifunctional hemolysin/adenylate cyclase {ECO:0000313|EMBL:ATZ22547.1};
GN Name=cya {ECO:0000313|EMBL:ATZ22547.1};
GN ORFNames=SLAV_03180 {ECO:0000313|EMBL:ATZ22547.1}, SLLC_01215
GN {ECO:0000313|EMBL:QUQ52389.1};
OS Streptomyces lavendulae subsp. lavendulae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ22547.1, ECO:0000313|Proteomes:UP000231791};
RN [1] {ECO:0000313|EMBL:ATZ22547.1, ECO:0000313|Proteomes:UP000231791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ22547.1,
RC ECO:0000313|Proteomes:UP000231791};
RA Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT 3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT angucycline-type antibiotic auricin.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QUQ52389.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Del-LP {ECO:0000313|EMBL:QUQ52389.1};
RA Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA Kalinowski J., Kormanec J.;
RT "The linear plasmid pSA3239 is essential for the replication of the
RT Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP024985; ATZ22547.1; -; Genomic_DNA.
DR EMBL; CP073778; QUQ52389.1; -; Genomic_DNA.
DR RefSeq; WP_030229211.1; NZ_JOEW01000010.1.
DR AlphaFoldDB; A0A2K8P722; -.
DR GeneID; 82162712; -.
DR KEGG; slx:SLAV_03180; -.
DR OrthoDB; 9805017at2; -.
DR Proteomes; UP000231791; Chromosome.
DR Proteomes; UP000676025; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProt.
DR Gene3D; 2.80.10.50; -; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.150.10.10; Serralysin-like metalloprotease, C-terminal; 1.
DR InterPro; IPR013431; Delta_60_rpt.
DR InterPro; IPR047589; DUF11_rpt.
DR InterPro; IPR018511; Hemolysin-typ_Ca-bd_CS.
DR InterPro; IPR001343; Hemolysn_Ca-bd.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR001434; OmcB-like_DUF11.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR NCBIfam; TIGR01451; B_ant_repeat; 1.
DR NCBIfam; TIGR02608; delta_60_rpt; 7.
DR PANTHER; PTHR38340; S-LAYER PROTEIN; 1.
DR PANTHER; PTHR38340:SF1; S-LAYER PROTEIN; 1.
DR Pfam; PF01345; DUF11; 1.
DR Pfam; PF17164; DUF5122; 7.
DR Pfam; PF00353; HemolysinCabind; 3.
DR PRINTS; PR00313; CABNDNGRPT.
DR SUPFAM; SSF101908; Putative isomerase YbhE; 2.
DR PROSITE; PS00330; HEMOLYSIN_CALCIUM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000231791};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 446..562
FT /note="DUF11"
FT /evidence="ECO:0000259|Pfam:PF01345"
FT REGION 540..562
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 678 AA; 66305 MW; ED170C7977BE507C CRC64;
MPHAHPRPVR PRRGPGGRAG LPAALGLVLV LLLPGTALAA PGDLDPSFGP DGRVTTVFPG
YAEGHDVARQ ADGKLVVTGL SQDGFALARY NTNGTLDTTF DGDGRVTSDF GGGAHVANAV
AVQPSDGKIV VAGTTEVPGE EGGCCFFSVA RYNTDGSLDA GFGNGGLVRV DEFGGSADGA
DVAVQPDGRI IAAGKGAGGG FALVRLTTGG SLDPSLGGDG AVVAGFTPAS PQDAGGTARG
MALQPDGKVL LVGYVGNTAF DIGVARYNTN GTLDTTFSGD GMVTADFGGT EFGNAVAVQP
DGKVVAAGDG GAGIALLRYN ADGSPDTGFG TGGRRSVAFP GDGGGASALA LQPNGKIVIA
GQADDPNSSE ANDFGVARFN TDGTVDTGFG GDGFVVTGFG DFDAARGVLV QPDGKIVAAG
YTAGSAFALA RYEGGDGTPP PPPGADLSVT RTTAATVSIG DRASYTVRVS NSAASTATAT
GVTLSDTLSG AGVTLTSATA SQGTCTTTAT AATCALGTLA PGASATVTVT AEPRATGTLT
GTARATATQP DPNASDNTAT STTTVNNARG CTVIGTSGAD TLNGGYANDV ICALGGNDTV
RASYGNDTVY GGYGNDNIDG GFGDDTLDGG PGTDTLTGYY GNDRLITTDG VAGNDTANGG
SGTDTCTTDP GDTRISCP
//
