ID A0A2K8P9Z7_STRLA Unreviewed; 889 AA.
AC A0A2K8P9Z7;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=SapB synthase {ECO:0000313|EMBL:QUQ52299.1};
DE EC=2.7.-.- {ECO:0000313|EMBL:QUQ52299.1};
DE SubName: Full=Serine/threonine-protein kinase PknA {ECO:0000313|EMBL:ATZ22455.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:ATZ22455.1};
GN Name=pknA1 {ECO:0000313|EMBL:ATZ22455.1};
GN Synonyms=ramC {ECO:0000313|EMBL:QUQ52299.1};
GN ORFNames=SLAV_02655 {ECO:0000313|EMBL:ATZ22455.1}, SLLC_00685
GN {ECO:0000313|EMBL:QUQ52299.1};
OS Streptomyces lavendulae subsp. lavendulae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ22455.1, ECO:0000313|Proteomes:UP000231791};
RN [1] {ECO:0000313|EMBL:ATZ22455.1, ECO:0000313|Proteomes:UP000231791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ22455.1,
RC ECO:0000313|Proteomes:UP000231791};
RA Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT 3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT angucycline-type antibiotic auricin.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QUQ52299.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Del-LP {ECO:0000313|EMBL:QUQ52299.1};
RA Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA Kalinowski J., Kormanec J.;
RT "The linear plasmid pSA3239 is essential for the replication of the
RT Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP024985; ATZ22455.1; -; Genomic_DNA.
DR EMBL; CP073778; QUQ52299.1; -; Genomic_DNA.
DR RefSeq; WP_030237052.1; NZ_JOEW01000034.1.
DR AlphaFoldDB; A0A2K8P9Z7; -.
DR GeneID; 82162622; -.
DR KEGG; slx:SLAV_02655; -.
DR OrthoDB; 1492512at2; -.
DR Proteomes; UP000231791; Chromosome.
DR Proteomes; UP000676025; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd04791; LanC_SerThrkinase; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR007822; LANC-like.
DR InterPro; IPR000719; Prot_kinase_dom.
DR NCBIfam; NF038150; lanthi_synth_IV; 1.
DR PANTHER; PTHR43671:SF13; LD04361P; 1.
DR PANTHER; PTHR43671; SERINE/THREONINE-PROTEIN KINASE NEK; 1.
DR Pfam; PF05147; LANC_like; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR01950; LANCSUPER.
DR SMART; SM01260; LANC_like; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF158745; LanC-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ATZ22455.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000231791};
KW Transferase {ECO:0000313|EMBL:ATZ22455.1}.
FT DOMAIN 219..494
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 482..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 889 AA; 94847 MW; 60242E973734F4B2 CRC64;
MTSHATEVDL EDLLRRALEA TGEGARWSTD ADEMWCRLTP LSTTQRAQGW KLHVSATSAS
APAVLAKALD VLLREGSAFK FARSLEQVSA LNSRATPRGS SGKFITVYPR SDTDAARIAL
ELHRATTGLA GPRILSDQPY AVNSLVHYRY GAFVARQRLS DQGLLVWFYE DPDGNPVEDV
RTGRYSPPSW AVSPFPASVP APPRTEEAPT GPVLLGGRFS VREAIRHTNK GGVYRGTDAI
TGAPVVIKEA RPHVEADASG SDVRDWLRAE ARTLENLAGT GLAPEPVAMF EHGGHLFLAQ
EEIPGVPLRN WVAEHFRDVG SERYRADALA QAGRLVDLLA AAHACGCVLR DFTPGNIMVR
PDGELRLIDL ELAVLKDDAA LPTTVGTPGF SAPERLAGAP VSPTADYYSL GATVCFVLAG
KVPHLLPEEP AARSAEQRLA EWLTACEGTL PLPDGLPGMI LGLMKDDPAE RWDPARARTA
LRRTGSPLPG HPAAGPTGKD PGDATAASVA GIVDHLVESM TPRDERRLWP VSTMAGETDP
CTVQQGAAGV LAVLTRYYEL TGDPRLPERI STAGHWIAAR TDTRSTRPGL HFGGRGTAWA
LYDAGRALDD RALMDHALAL ALAPQEPTPS HDVTHGSAGS GLAAAHLWHR TGDPRLAALV
ADAADRLAAA ARPEPTGVSW PVPAEAVAKE AGKRYLGFAH GTSGIGCFLL AAAAVTDRRE
HLDLALAAGE ELVATALTVG ETAQWPAQAG DVPTAPYWCH GSAGIGSFLV RLWQTTGDDR
FGDLARRAAR AVVERASRAP LTQCHGLAGN GDFLLDMATA TGDPAYRTSA EDLARFIVAE
RAHRDRHVVF PNEYGDVSTG WSDGSAGILA FLLRTRHTDS RLWMIQQPG
//
