ID A0A2K8PA64_STRLA Unreviewed; 514 AA.
AC A0A2K8PA64;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Tripeptidyl aminopeptidase {ECO:0000313|EMBL:ATZ22633.1};
DE EC=3.4.14.- {ECO:0000313|EMBL:ATZ22633.1};
GN Name=tap3 {ECO:0000313|EMBL:ATZ22633.1};
GN Synonyms=tap_1 {ECO:0000313|EMBL:QUQ52475.1};
GN ORFNames=SLAV_03625 {ECO:0000313|EMBL:ATZ22633.1}, SLLC_01660
GN {ECO:0000313|EMBL:QUQ52475.1};
OS Streptomyces lavendulae subsp. lavendulae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ22633.1, ECO:0000313|Proteomes:UP000231791};
RN [1] {ECO:0000313|EMBL:ATZ22633.1, ECO:0000313|Proteomes:UP000231791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ22633.1,
RC ECO:0000313|Proteomes:UP000231791};
RA Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT 3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT angucycline-type antibiotic auricin.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QUQ52475.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Del-LP {ECO:0000313|EMBL:QUQ52475.1};
RA Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA Kalinowski J., Kormanec J.;
RT "The linear plasmid pSA3239 is essential for the replication of the
RT Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S33 family.
CC {ECO:0000256|ARBA:ARBA00010088}.
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DR EMBL; CP024985; ATZ22633.1; -; Genomic_DNA.
DR EMBL; CP073778; QUQ52475.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8PA64; -.
DR KEGG; slx:SLAV_03625; -.
DR Proteomes; UP000231791; Chromosome.
DR Proteomes; UP000676025; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR013595; Pept_S33_TAP-like_C.
DR PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR PANTHER; PTHR43248:SF29; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF08386; Abhydrolase_4; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Aminopeptidase {ECO:0000313|EMBL:ATZ22633.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ATZ22633.1};
KW Protease {ECO:0000313|EMBL:ATZ22633.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000231791};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..514
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014719997"
FT DOMAIN 97..271
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT DOMAIN 403..501
FT /note="Peptidase S33 tripeptidyl aminopeptidase-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08386"
SQ SEQUENCE 514 AA; 54933 MW; 92EFBD4FF3082FEE CRC64;
MHLFRKPVRW AATAACGLLA LAALPAPTAA AAPGGAPAVP GRYAHQRLDW RPCPSGSLEC
ASMTVPRDWY HPGAGADLTV AVSRHRAADP AARRGVLMMA AGGPGASGLG RPEGLASYAP
KLAAAYDIVG FDQRGVGAST NVVCSDQDTV DAMFGGGDLR DRSPEAVDGT LERARKFVRD
CRANSGGLLP FITTDQAVRD MDLYRSLLGT ERISFYGPSY ATFLGAQYAR TFPRRVDRMV
LDSAIDAVGG WEEFMTGQPL SFQRRFEEDF LPWLALHDDV YHLGRTAQEA KDGYERLRAS
LRDRPLDLEG TPVTPDRLDA AATSIIYSGS RFPDLAAVLG LLRDPDAAPP AARQALAAKL
RHPLGAAFAA DFFSVVCQDT PWTRDLGRWV ARSEADSRTH PMIGARELSY AAVCAQWPRS
RAPEPAGNGR ELPPVLMLGS THDPATYYEG AVRAHQRLAG SRLITVHGGD HGVYQAGNAC
VDGYVEGFLA DGRMPAADAS CEGNPLPVPA AARG
//
