ID   A0A2K8PIK0_STRLA        Unreviewed;       611 AA.
AC   A0A2K8PIK0;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Prolyl endopeptidase {ECO:0000313|EMBL:ATZ25930.1};
DE            EC=3.4.21.26 {ECO:0000313|EMBL:ATZ25930.1};
DE   SubName: Full=Tol-Pal system protein TolB {ECO:0000313|EMBL:QUQ55759.1};
GN   Name=tolB_2 {ECO:0000313|EMBL:QUQ55759.1};
GN   ORFNames=SLAV_20535 {ECO:0000313|EMBL:ATZ25930.1}, SLLC_18640
GN   {ECO:0000313|EMBL:QUQ55759.1};
OS   Streptomyces lavendulae subsp. lavendulae.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ25930.1, ECO:0000313|Proteomes:UP000231791};
RN   [1] {ECO:0000313|EMBL:ATZ25930.1, ECO:0000313|Proteomes:UP000231791}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ25930.1,
RC   ECO:0000313|Proteomes:UP000231791};
RA   Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA   Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA   Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT   "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT   3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT   angucycline-type antibiotic auricin.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:QUQ55759.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Del-LP {ECO:0000313|EMBL:QUQ55759.1};
RA   Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA   Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA   Kalinowski J., Kormanec J.;
RT   "The linear plasmid pSA3239 is essential for the replication of the
RT   Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL   Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP024985; ATZ25930.1; -; Genomic_DNA.
DR   EMBL; CP073778; QUQ55759.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K8PIK0; -.
DR   KEGG; slx:SLAV_20535; -.
DR   Proteomes; UP000231791; Chromosome.
DR   Proteomes; UP000676025; Chromosome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 2.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR001375; Peptidase_S9.
DR   PANTHER; PTHR42776:SF28; DIPEPTIDYL-PEPTIDASE 5; 1.
DR   PANTHER; PTHR42776; SERINE PEPTIDASE S9 FAMILY MEMBER; 1.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF82171; DPP6 N-terminal domain-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ATZ25930.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000231791}.
FT   DOMAIN          408..609
FT                   /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00326"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          67..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..83
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   611 AA;  65830 MW;  9D29F69D4CF99824 CRC64;
     MEGMTSDSDL TPGAAAETPE MPDWEKRFRA PRVGLPDWAE DAPDRSLFVS NATGTYELYA
     WDRATGTQRQ ATDRPNGTTD GTLSPDGEWI WWFSDTDGDE FGTWVRQPFA GGPDEPATPG
     LEPSYPAGLA LGRDGTAVVG RSTDEDGSTI HVVRPDGSAP AVIYRHRESA GVGDLSHDGT
     LLAIEHTEHG DAMHSALRVV TLDGATVAEL DDSRGGTVEL GLEVLGFAPV AGDTRLLVGH
     QRRGRWEPMV WDVATGAQED LAVELPGDVS AEWYPDGSAL LVAHSFEARS ELWRYDLAAR
     ELVRVDTPPG SVSGATARPD GTVEYQWSSA AEPASVRSTA GGIVLDPPGF RPPGSVPVED
     VWVEGPGGRI HALAQRPVGH GEGPFPTIFE IHGGPTWHDS DSFLATPAAW LDHGFAVVRV
     NYRGSTGYGR EWTDALKHRV GLIELEDVSA VREWAVTSGL ADPARLVLSG GSWGGYLTLL
     GIGTRPDDWA VGLAAVPVAD YVTAYHDEME ALKALDRTLF GGTPEEVPER FEASSPLTYV
     DAVKAPVHIA AGVNDPRCPI RQIDNYVDRL AARGAVHEVY RYDAGHGSLV VEERIKQVRM
     DLEFALKHLP R
//