ID A0A2K8PJC4_STRLA Unreviewed; 329 AA.
AC A0A2K8PJC4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Bifunctional ligase/repressor BirA {ECO:0000313|EMBL:ATZ26210.1};
DE EC=6.3.4.15 {ECO:0000313|EMBL:ATZ26210.1};
GN Name=birA2 {ECO:0000313|EMBL:ATZ26210.1};
GN ORFNames=SLAV_21970 {ECO:0000313|EMBL:ATZ26210.1}, SLLC_20085
GN {ECO:0000313|EMBL:QUQ56039.1};
OS Streptomyces lavendulae subsp. lavendulae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ26210.1, ECO:0000313|Proteomes:UP000231791};
RN [1] {ECO:0000313|EMBL:ATZ26210.1, ECO:0000313|Proteomes:UP000231791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ26210.1,
RC ECO:0000313|Proteomes:UP000231791};
RA Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT 3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT angucycline-type antibiotic auricin.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QUQ56039.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Del-LP {ECO:0000313|EMBL:QUQ56039.1};
RA Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA Kalinowski J., Kormanec J.;
RT "The linear plasmid pSA3239 is essential for the replication of the
RT Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP024985; ATZ26210.1; -; Genomic_DNA.
DR EMBL; CP073778; QUQ56039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8PJC4; -.
DR KEGG; slx:SLAV_21970; -.
DR Proteomes; UP000231791; Chromosome.
DR Proteomes; UP000676025; Chromosome.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001034; DeoR_HTH.
DR InterPro; IPR013196; HTH_11.
DR InterPro; IPR028349; PafC.
DR InterPro; IPR018356; Tscrpt_reg_HTH_DeoR_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR026881; WYL_dom.
DR PANTHER; PTHR34580; -; 1.
DR PANTHER; PTHR34580:SF1; PROTEIN PAFB; 1.
DR Pfam; PF08279; HTH_11; 1.
DR Pfam; PF13280; WYL; 1.
DR PIRSF; PIRSF016838; PafC; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00894; HTH_DEOR_1; 1.
DR PROSITE; PS51000; HTH_DEOR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Ligase {ECO:0000313|EMBL:ATZ26210.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000231791};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..59
FT /note="HTH deoR-type"
FT /evidence="ECO:0000259|PROSITE:PS51000"
SQ SEQUENCE 329 AA; 35025 MW; 1C6F924A30A3358C CRC64;
MNDTPARLLT LLSLLQTPRE WPGSELAARL EVSARTIRRD IERLRVLGYP VEASLGAEGG
YRLVAGAAMP PLLLDDEEAV AIAVGLRAGA GHAIEGVEEA SVRALAKLEQ VLPARLRHRV
GALQSATVAL TRGDGPSVDP RTLTTMAGAV AGPERLRFAY RARDGAGTRR LVEPYRLVST
GIRWYLVAYD LEREDWRTFR VDRVSEPFAT GARFVPRELP MEAAAFVRRG LQGGETYPVE
VSFAAPPQEL PGWLRESAVA EGEGSRVCFE SGDAPEWVAA RLALTGVPFT VRGPESLVRS
ARTLAGRLAA GAGAAAGTGG PEGDGAGRA
//
