ID A0A2K8PKU9_STRLA Unreviewed; 331 AA.
AC A0A2K8PKU9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Probable cell division protein WhiA {ECO:0000256|HAMAP-Rule:MF_01420};
GN Name=whiA {ECO:0000256|HAMAP-Rule:MF_01420,
GN ECO:0000313|EMBL:ATZ27356.1};
GN ORFNames=SLAV_27830 {ECO:0000313|EMBL:ATZ27356.1}, SLLC_25970
GN {ECO:0000313|EMBL:QUQ57183.1};
OS Streptomyces lavendulae subsp. lavendulae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ27356.1, ECO:0000313|Proteomes:UP000231791};
RN [1] {ECO:0000313|EMBL:ATZ27356.1, ECO:0000313|Proteomes:UP000231791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ27356.1,
RC ECO:0000313|Proteomes:UP000231791};
RA Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT 3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT angucycline-type antibiotic auricin.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QUQ57183.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Del-LP {ECO:0000313|EMBL:QUQ57183.1};
RA Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA Kalinowski J., Kormanec J.;
RT "The linear plasmid pSA3239 is essential for the replication of the
RT Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cell division and chromosome segregation.
CC {ECO:0000256|HAMAP-Rule:MF_01420}.
CC -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000256|HAMAP-
CC Rule:MF_01420}.
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DR EMBL; CP024985; ATZ27356.1; -; Genomic_DNA.
DR EMBL; CP073778; QUQ57183.1; -; Genomic_DNA.
DR RefSeq; WP_030237199.1; NZ_JOEW01000036.1.
DR AlphaFoldDB; A0A2K8PKU9; -.
DR GeneID; 82167511; -.
DR KEGG; slx:SLAV_27830; -.
DR OrthoDB; 5197218at2; -.
DR Proteomes; UP000231791; Chromosome.
DR Proteomes; UP000676025; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR Gene3D; 3.10.28.10; Homing endonucleases; 1.
DR HAMAP; MF_01420; HTH_type_WhiA; 1.
DR InterPro; IPR027434; Homing_endonucl.
DR InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR InterPro; IPR003802; Sporulation_regulator_WhiA.
DR InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR NCBIfam; TIGR00647; DNA_bind_WhiA; 1.
DR PANTHER; PTHR37307; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR PANTHER; PTHR37307:SF1; CELL DIVISION PROTEIN WHIA-RELATED; 1.
DR Pfam; PF02650; HTH_WhiA; 1.
DR Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR Pfam; PF10298; WhiA_N; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW Cell division {ECO:0000256|ARBA:ARBA00022618, ECO:0000256|HAMAP-
KW Rule:MF_01420};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01420}; Reference proteome {ECO:0000313|Proteomes:UP000231791}.
FT DOMAIN 19..104
FT /note="Sporulation transcription regulator WhiA N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10298"
FT DOMAIN 127..218
FT /note="WhiA LAGLIDADG-like"
FT /evidence="ECO:0000259|Pfam:PF14527"
FT DOMAIN 221..303
FT /note="Sporulation regulator WhiA C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02650"
FT REGION 312..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 331 AA; 35243 MW; A8D008824BAD4881 CRC64;
MAMTPAVKDE ISRLPVTRTC CRKAEVSAIL RFAGGLHLVS GRIVIEAELD TGIAARRLRK
DILEIFGHSS DLVVMAPGGL RRGSRFVVRV VAGGDQLARQ TGLVDGRGRP IRGLPPQVVS
GATCDAEAAW RGAFLAHGSL TEPGRSSSLE VTCPGPEAAL ALVGAARRLS IAAKAREVRG
VDRVVVRDGD AIGALLTRLG AHESVLAWEE RRMRREVRAT ANRLANFDDA NLRRSARAAV
AAGARVQRAL EILGEEVPEH LAAAGRLRME HKQASLEELG ALADPPLTKD AVAGRIRRLL
AMADKRAQDL GIPGTESNLD LSEELADNMA G
//
