ID A0A2K8PNB2_STRLA Unreviewed; 344 AA.
AC A0A2K8PNB2;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Tunicamycin resistance protein {ECO:0000313|EMBL:ATZ28246.1};
GN Name=tmrB3 {ECO:0000313|EMBL:ATZ28246.1};
GN ORFNames=SLAV_32370 {ECO:0000313|EMBL:ATZ28246.1}, SLLC_30540
GN {ECO:0000313|EMBL:QUQ58074.1};
OS Streptomyces lavendulae subsp. lavendulae.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=58340 {ECO:0000313|EMBL:ATZ28246.1, ECO:0000313|Proteomes:UP000231791};
RN [1] {ECO:0000313|EMBL:ATZ28246.1, ECO:0000313|Proteomes:UP000231791}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCM 3239 {ECO:0000313|EMBL:ATZ28246.1,
RC ECO:0000313|Proteomes:UP000231791};
RA Busche T., Novakova R., Al'Dilaimi A., Homerova D., Feckova L.,
RA Rezuchova B., Mingyar E., Csolleiova D., Bekeova C., Winkler A.,
RA Sevcikova B., Kalinowski J., Kormanec J., Ruckert C.;
RT "Complete genome sequence of Streptomyces lavendulae subsp. lavendulae CCM
RT 3239 (formerly 'Streptomyces aureofaciens CCM 3239'), the producer of the
RT angucycline-type antibiotic auricin.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QUQ58074.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Del-LP {ECO:0000313|EMBL:QUQ58074.1};
RA Novakova R., Ruckert C., Knirschova R., Feckova L., Busche T.,
RA Csolleiova D., Homerova D., Rezuchova B., Javorova R., Sevcikova B.,
RA Kalinowski J., Kormanec J.;
RT "The linear plasmid pSA3239 is essential for the replication of the
RT Streptomyces lavendulae subsp. lavendulae CCM 3239 chromosome.";
RL Submitted (APR-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC {ECO:0000256|ARBA:ARBA00005582}.
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DR EMBL; CP024985; ATZ28246.1; -; Genomic_DNA.
DR EMBL; CP073778; QUQ58074.1; -; Genomic_DNA.
DR RefSeq; WP_030232840.1; NZ_JOEW01000020.1.
DR AlphaFoldDB; A0A2K8PNB2; -.
DR GeneID; 82168408; -.
DR KEGG; slx:SLAV_32370; -.
DR OrthoDB; 9799092at2; -.
DR Proteomes; UP000231791; Chromosome.
DR Proteomes; UP000676025; Chromosome.
DR CDD; cd02883; Nudix_Hydrolase; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR020476; Nudix_hydrolase.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43046; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR PANTHER; PTHR43046:SF12; GDP-MANNOSE MANNOSYL HYDROLASE; 1.
DR Pfam; PF13671; AAA_33; 1.
DR Pfam; PF00293; NUDIX; 1.
DR PRINTS; PR00502; NUDIXFAMILY.
DR SUPFAM; SSF55811; Nudix; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000231791}.
FT DOMAIN 197..327
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 344 AA; 38237 MW; 568117EB0548273D CRC64;
MIVWINGTFG AGKTSTAREL AGLLPDGTLY DPELIGDALR RLLPHKRLAE VCDYQDLPSW
RRLVVDAAAA MLAELGGVLV VPMTLLRQEY RDEIFGALAA RRIPVRHVLL APAETILRER
IARRQETEPE PADPRDRTWA YDHIPVYRQA LGWLTADAHV IDNGPLTARE TAERIAEAVR
TDAAGICDIV QTPEPTRETV AAGVLLFDDQ DRVLLVDPTY KPGWEFPGGV VEAGEAPACA
GVREVAEELG LTLEQVPGLL VVDWEPPRSP AYGGLRLLFD GGRLTRQDAE RLRLPGPELR
AWRFVTETEA AGLLPPQRYE RLRWALRARE RGHPLYLEAG RPTP
//
