ID   A0A2K8T2V5_9NOSO        Unreviewed;       481 AA.
AC   A0A2K8T2V5;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Multidrug efflux pump subunit AcrA {ECO:0000313|EMBL:AUB42024.1};
GN   ORFNames=COO91_08123 {ECO:0000313|EMBL:AUB42024.1};
OS   Nostoc flagelliforme CCNUN1.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=2038116 {ECO:0000313|EMBL:AUB42024.1, ECO:0000313|Proteomes:UP000232003};
RN   [1] {ECO:0000313|EMBL:AUB42024.1, ECO:0000313|Proteomes:UP000232003}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCNUN1 {ECO:0000313|EMBL:AUB42024.1,
RC   ECO:0000313|Proteomes:UP000232003};
RA   Shang J.;
RT   "Complete genome of a free-living desiccation-tolerant cyanobacterium and
RT   its photosynthetic adaptation to extreme terrestrial habitat.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000256|ARBA:ARBA00007613}.
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DR   EMBL; CP024785; AUB42024.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K8T2V5; -.
DR   KEGG; nfl:COO91_08123; -.
DR   OrthoDB; 8439633at2; -.
DR   Proteomes; UP000232003; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR   InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR   InterPro; IPR022275; NHPM_bacteriocin_SS_HylD.
DR   InterPro; IPR003423; OMP_efflux.
DR   NCBIfam; TIGR03794; NHLM_micro_HlyD; 1.
DR   PANTHER; PTHR30386:SF28; BLR1709 PROTEIN; 1.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   Pfam; PF13533; Biotin_lipoyl_2; 1.
DR   Pfam; PF13437; HlyD_3; 1.
DR   Pfam; PF02321; OEP; 1.
DR   PRINTS; PR01490; RTXTOXIND.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000232003};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        35..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          73..120
FT                   /note="Membrane fusion protein biotin-lipoyl like"
FT                   /evidence="ECO:0000259|Pfam:PF13533"
FT   COILED          106..162
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          216..310
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   481 AA;  53575 MW;  43548D2C57374068 CRC64;
     MLHEKQSLFR KESLERLSSP ERLDQLMHVV SPRSWLPLVG LGSIIGVALI WSIFGRIPIT
     VEGKGVLIFP RQVVPVQSKS SGQLLALNIK VGDVVKKGDV LATVDQVDLR KQLQLASGKL
     VQLEEQDRNA SLLQGQRQQL DTRAIQEQRQ TLEQRLKIVQ DLTPVLREKG LVSIGRDRLN
     LQRRLQTLQG LLPTHKKRLE NRQRLLAEGA IPDDVVLEAR QQYDDARASI DEAQSQLKRL
     DVKEADAQQQ YLSNLNEIKN IQAQLQEQNS KVASQAQQDL QTVTTRKNEI QELKREIAKL
     QQQLGDNSEI ASQYSGRILE ITLTPGQVVS PGTRLATIEA ENPKKKLVSV TYFPVSDGKK
     IQPGMAIQIT PQTVKRERYG GIAGNISSLS KFPITKEAAA SEIGNSELVE TLVSEKQEAL
     IQVFSNLELN SSTPTGYKWS SSTGPELKIS SGTTTVARVK VEERAPITYI FPILRSLSGI
     Y
//