ID   A0A2K8VBY2_9FLAO        Unreviewed;       744 AA.
AC   A0A2K8VBY2;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Aminopeptidase {ECO:0000313|EMBL:AUC15172.1};
GN   ORFNames=BTO06_08480 {ECO:0000313|EMBL:AUC15172.1};
OS   Tenacibaculum sp. SZ-18.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Tenacibaculum.
OX   NCBI_TaxID=754423 {ECO:0000313|EMBL:AUC15172.1, ECO:0000313|Proteomes:UP000232695};
RN   [1] {ECO:0000313|EMBL:AUC15172.1, ECO:0000313|Proteomes:UP000232695}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SZ-18 {ECO:0000313|EMBL:AUC15172.1,
RC   ECO:0000313|Proteomes:UP000232695};
RA   Kumagai Y., Yoshizawa S., Kogure K., Iwasaki W.;
RT   "Trade-off between light-utilization and light-protection in marine
RT   flavobacteria.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP019335; AUC15172.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K8VBY2; -.
DR   OrthoDB; 9814383at2; -.
DR   Proteomes; UP000232695; Chromosome.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09604; M1_APN_like; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR11533:SF303; AMINOPEPTIDASE N; 1.
DR   PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:AUC15172.1};
KW   Hydrolase {ECO:0000313|EMBL:AUC15172.1};
KW   Protease {ECO:0000313|EMBL:AUC15172.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000232695};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..744
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5014765565"
FT   DOMAIN          370..572
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
SQ   SEQUENCE   744 AA;  86101 MW;  3DC4B8F2420B480A CRC64;
     MKKLFYVFFS LFLITGSTYA QETEKEKTPQ KGHIDENKFR QLKDVLATPN DQRTASGAPG
     HQYTQQKVDY VMNLRLDEAN DKLYGDETIT YHNNSKDHLE YLWLQLDQNM RAPNSQTPLA
     QSKGASGWQT PAQFVDDNMG KKKDFGFKIE AVKYEDGRDL SHTINRTMMR VNLPEPLAPG
     STFTFKIKWN YLINNVVDDG GRSGVEYFKD GNKAFIIAQF FPRLCVYNNV EGWQNMQFWG
     RSEFALEFGD YDVKLTVPAD HILEATGELQ NEKEVLSKEQ RKRLEKARKS YKDPVVIVTQ
     KEAEANEKKR SSKTKTWHFK AKNVRDYAFA TSRKYIWDAM AVDINGKSVM AVSLYPKEGN
     PLWEEHSTRT VANTLEEYSK LTFDYPYPKA VSVNANDGMG MEYPMICFNF GRPDADGTYS
     DRLKSGMIGV IIHEVGHNFF PMIVNSDERQ WTWMDEGLNS FVQILAEFDY DAKLFAQNPT
     KNITRYMSFD QSNLSPIMSQ GDYVQNFGPN AYTKPAAGLY MLRKTIMGPE LFDHAFRTYS
     KRWMFKHPTP ADFFRTMEDA SGMDLDWFWR GWFYTTDNCD IGIKEVKPIY LTDKPNERTK
     QLQAQYPGYF ARLGKLVFLT TNKEDANPAD VEAYINDLPA DKKANLEKLP KFMYQVEFEK
     PGGLVMPIIV ELTYADGTKK REVFPAQIWN KDDNKVFRVF TSTKEIKKIT VDPDEETADV
     DMSNNAWPKK EESKFNKFKN KMKD
//