ID   A0A2K8VFI1_9FLAO        Unreviewed;      1040 AA.
AC   A0A2K8VFI1;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   ORFNames=BTO06_14985 {ECO:0000313|EMBL:AUC16374.1};
OS   Tenacibaculum sp. SZ-18.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Tenacibaculum.
OX   NCBI_TaxID=754423 {ECO:0000313|EMBL:AUC16374.1, ECO:0000313|Proteomes:UP000232695};
RN   [1] {ECO:0000313|EMBL:AUC16374.1, ECO:0000313|Proteomes:UP000232695}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SZ-18 {ECO:0000313|EMBL:AUC16374.1,
RC   ECO:0000313|Proteomes:UP000232695};
RA   Kumagai Y., Yoshizawa S., Kogure K., Iwasaki W.;
RT   "Trade-off between light-utilization and light-protection in marine
RT   flavobacteria.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
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DR   EMBL; CP019335; AUC16374.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K8VFI1; -.
DR   OrthoDB; 9810135at2; -.
DR   Proteomes; UP000232695; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   Gene3D; 1.10.3170.10; Recbcd, chain B, domain 2; 1.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF64; ATP-DEPENDENT DNA HELICASE REP; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000232695}.
FT   DOMAIN          1..464
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   DOMAIN          477..728
FT                   /note="UvrD-like helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51217"
FT   BINDING         12..19
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   1040 AA;  120842 MW;  38B53849DF625221 CRC64;
     MEVSPSFQIF NASAGSGKTF TLVKEYLKVV LQSSDVFYFQ KILAITFTNK AAGEMKERVM
     KSLSDAAEEV ENDIIGQILQ ETTLDKTTVK ERSTKVLNAI LQNYSDFSIT TIDSFTHKII
     KNFAFDLGLT LNFEVEMDAV SLLNEAVDIL ISKIGTSNEL TNLLIDFSLS KIDEDKSWDI
     SLELKEFSKI LLNEDDVKHF RILQQRTTSD FINLKHKLQN HRVLVEKRLK EIGIEGLEII
     QTAGLDHKDF YYSLLPKHFA ALKNNPSSAK FFDQSKLKER IEENLFYSKT KSDHIKSIIE
     GILPQLLKLY TESENLFKDL VLQKLTLKSL IPLAVLNTIN KELSNLKEEN NIRLNAEFNQ
     LISDNIKDQP TPFIYERIGE RFMHYFIDEM QDTSVLQWEN LIPLVDNALA QGYSSLLLVG
     DAKQAIYRWR GGKAEQFINL SNENYKVFQA DKSIEILDTN YRSYSEVIQF NNDFFQHVSG
     YLGNSEYQNL FIEGNKQLKN KKKGGQVTIS FLEKEEDKEA EKKKYPQKVF ETINDLRSQY
     ALNEIAVLVR KKSEGVQVAN YLSEKEIPLI SSETLLLKNS EKVNFISNLI QLILQSDNEE
     LKFEVLHFLF HHLSIEEEIH TFLNQLIKKD IGTFFAELQV YNIHFQINDY FELPLYDKVE
     YIIRSFNLIE DSDAYVQFFL DIVLDQQNKG NDVHDFMEYW NLKKDLLSIV TSEDAEAVHI
     MTIHKSKGLE FPVVIFPYDL DVYRQVKPKV WFDSIPESYE GFSELLIDFN KSIGYINERG
     SELYDRQIQE LELDNFNLLY VALTRAVEQL HIITEKRLSK SGENTNYYSG LFISFLKKLG
     LWNDNEIEYK FGDCNRISSQ ERTKSEIQIQ EKFITTPWQS HNILLLASDS KLWDTDQEES
     VQYGNLMHAI LAEIHSVDDL ESVFHFYEMR GDISATLLKT IKNLVVKIVG HDELEKYFSD
     EVQVYNEKDI LTQQSTIIIP DRLVFKNDLV TIIDYKTGIE NDSHVYQIKH YGNELEKLGF
     NIDKKLLVYI NDEVLVKEID
//