ID A0A2K8X4T1_9FLAO Unreviewed; 659 AA.
AC A0A2K8X4T1;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CW736_00320 {ECO:0000313|EMBL:AUC77945.1};
OS Nonlabens sp. MB-3u-79.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=2058134 {ECO:0000313|EMBL:AUC77945.1, ECO:0000313|Proteomes:UP000232401};
RN [1] {ECO:0000313|EMBL:AUC77945.1, ECO:0000313|Proteomes:UP000232401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB-3u-79 {ECO:0000313|EMBL:AUC77945.1,
RC ECO:0000313|Proteomes:UP000232401};
RA Collins E., Ducluzeau A.-L.;
RT "Pharmacopeia of the Arctic Ocean.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP025116; AUC77945.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8X4T1; -.
DR KEGG; nob:CW736_00320; -.
DR OrthoDB; 9781208at2; -.
DR Proteomes; UP000232401; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AUC77945.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000232401};
KW Transferase {ECO:0000313|EMBL:AUC77945.1}.
FT DOMAIN 55..123
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 126..178
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 308..379
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 381..433
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 451..659
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 6..33
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 424..451
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 659 AA; 75757 MW; F7606B4FF9C700E1 CRC64;
MDSNKIKIYE RALAREKAAR KEAERILEEK SKELYLKSKE LEISNEKLYK LLQTKTSELK
GVFGNMLDAY VVMDLKGLVL SMNEAAQKLL GYSLEGKLNL FSMVLPEERL KVLSSFQELM
ENGSIKDFQV KIIIASGLTR MVHINASIVY NGKNQPVAAQ GIVRDITEEK AENQLLLESQ
NRLSTLISHL HSAVLLEDED RNVVVTNQRF CEFFKIPLDP KEMIGINFAD AAEESKHLFK
NPSEFVKRIN FLTKEKNQVF SDELFLKDGS ILERDFIPIY EEGEYQGHLW TYRDVTLKKK
YHEGIEAERQ KYSSIIANMN LGLIEVDNED RIIMENQSLE QMSGYSKKEL IGRLYSDMLI
VKEDQSILEN ENRKRLDGLS NSYEVRVKAK DGSIKHWLIS GAPNYNIKGQ VTGSIGIHLD
ITQLKSLELQ KENLLDKLEK SNEELQEYAH VVSHDLKSPL LSISALMSWI KDDNQGKLSH
DTLDNFKMID ATLEKMELLI SDILEYSSII NNNDSPTEVD LNNVMEDIVT LLHFPDHIVF
NVKKPLPKLI VDRVKIQQLF QNLISNAINY CEKERGFIEV DYQEGIDEYT FSLKDNGIGI
DKEYHQKIFQ IFQSLNEKEE STGIGLSIVK KIVDLYNGRI WLESSSGEGT TFFFTIKKY
//
