ID A0A2K8XAA2_9FLAO Unreviewed; 666 AA.
AC A0A2K8XAA2;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:AUC79837.1};
GN ORFNames=CW736_10900 {ECO:0000313|EMBL:AUC79837.1};
OS Nonlabens sp. MB-3u-79.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=2058134 {ECO:0000313|EMBL:AUC79837.1, ECO:0000313|Proteomes:UP000232401};
RN [1] {ECO:0000313|EMBL:AUC79837.1, ECO:0000313|Proteomes:UP000232401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB-3u-79 {ECO:0000313|EMBL:AUC79837.1,
RC ECO:0000313|Proteomes:UP000232401};
RA Collins E., Ducluzeau A.-L.;
RT "Pharmacopeia of the Arctic Ocean.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP025116; AUC79837.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8XAA2; -.
DR KEGG; nob:CW736_10900; -.
DR OrthoDB; 9769337at2; -.
DR Proteomes; UP000232401; Chromosome.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 2.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF00676; E1_dh; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000232401}.
FT DOMAIN 350..523
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 666 AA; 74784 MW; F21648F4CEC2EF6A CRC64;
MIDTDQTDLK KLYSNTLDHK VLIDLYKKML MPRLIEEKML ILLRQGRISK WFSGIGQEAI
SIGLTAAMQK DEYILPMHRN LGVFTSREIP LWKLFAQWQG KAEGFTKGRD RSFHFGTQEY
KIIGMISHLG PQLGVADGIA LAQKMNNTGK ATAVFTGEGG TSEGDFHEAL NVASVWSLPV
LFCIENNGYG LSTPTSEQYN CEHLADRALG YGMESHIIDG NNIIEVYTKI SAILNDMRER
PHPVLIEFKT FRRRGHEEAS GTKYVPDELL EYWEQRDPLS RFEKFLLEEH IISSDLIKNW
NKEFKKEIND GLDTAFAKAL PESTTELELA DVFAPHTFNQ VNPDSSSQNI RLIDAIKDGL
EEAMDAYDNL VIMGQDVAEY GGVFKITDGF VEKYGRERVR NTPICESAIV EAGMGLSIMG
MKAVVEMQFA DFVSSGFNPI VNYLAKSYYR WNQKADVVIR MPCGAGVGAG PFHSQTNESW
FYTVPGLKIV YPSTPADAKG LLIASIEDPN PVLFFEHKAL YRSIYDDVPD GYYNIELGKA
LNICVGNDAT IITFGAGVHW AKQLIKEENL SIDLIDLRTL VPLDKQAIIK SVQKTGRVLL
VTEDNLTGSV ISDIAAFISE ECFEYLDAPV MRLGSIDTPI PFEKGLENNY LPLQDLKEKL
KKLLKY
//
