ID A0A2K8XAR1_9FLAO Unreviewed; 954 AA.
AC A0A2K8XAR1;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CW736_11745 {ECO:0000313|EMBL:AUC79997.1};
OS Nonlabens sp. MB-3u-79.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=2058134 {ECO:0000313|EMBL:AUC79997.1, ECO:0000313|Proteomes:UP000232401};
RN [1] {ECO:0000313|EMBL:AUC79997.1, ECO:0000313|Proteomes:UP000232401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB-3u-79 {ECO:0000313|EMBL:AUC79997.1,
RC ECO:0000313|Proteomes:UP000232401};
RA Collins E., Ducluzeau A.-L.;
RT "Pharmacopeia of the Arctic Ocean.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP025116; AUC79997.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8XAR1; -.
DR KEGG; nob:CW736_11745; -.
DR OrthoDB; 5522855at2; -.
DR Proteomes; UP000232401; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 4.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 5.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 4.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 5.
DR SMART; SM00091; PAS; 5.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 5.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000232401}.
FT DOMAIN 81..111
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 141..193
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 201..243
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 341..383
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 545..596
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 617..669
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 670..724
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 742..954
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 318..345
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 954 AA; 110503 MW; 1C33BBCC0DF4F679 CRC64;
MTEITGFNFT EDDFTAADLV KFELIKSEEE EDLNNLAELF NHIVAAKAAK LSQEKEEFYS
KQLVLKELES DIFYNHFPCG YFSTDSNGII NKINTTLLGW LGYAKEDIIG KVTWQSLLSV
GGKMYFETHY SPLLQMQGFV QEISFEMVKK DKTRLPILIN TKQIRDENGK VQINYSTVFD
VSQRKSYEKE LLIAKRTAED QNELIEYTFR NASTPIYYVL EDASIYDFND IAAEKLGYTS
EELHTLKIYD LDKNYDEKKW ASEWAKLKAK KKITIETQQK KKDGTLIDVI ITANYVKYGD
LQLNCSYVLD ITEKKKRADE LKIANKELAF QNEEKEKRAE DLKLMDFAFK ESSTPIMLHL
QNGEFYSFND ALLNILGYTK EEFSKMNLLN VVTMDELACI SQWDEIKEKG TVVFDCHFER
KDGVLLDVEV SSNLIKYNKY EVNFCYINDI TEKKKAETEI YSMNELLQRQ TDCLLLATKS
AQLGIWDWDL ESDTLVWDEG MCKLYGIAAN KFKLIKEEWI ARLHEEDRTE IDNEIQLAIT
NKKEYNTEFR IVWSDSSIHY IRATGIVERV DGKPKRMIGV NWDVTAEKQS IQHLKLLESV
IVHTKDSILI TEAEPNDLPG PRMIFVNPAF EKMTGYTSEE VIGLTPRLLQ NEDTDRKELD
KLRTALNKWE PCEITVSNSR KNGEKFWNNF SVAPVANEKG WYTHWIAIER DVTKQIEATI
EKERMIKELL ENNRELKQFS YITTHNLRAP LTNLVLICKL ISREKIEDPS ILKLIEAFKT
STYQLNETLN DLINVLIVKE NTDLKLEELS VVEIMNKVKE SISETLRDSK AIIETDFSDM
PTVHFTKVYL ESIFLNLITN SIKYRHPERN PIVKIKTTKD AIGRTKLTFS DNGIGMDMSR
VKHKIFGFHQ RFHNNADSKG IGLFLIKSQI NALGGQIEVN SEVNIGTHFT ITFK
//
