ID A0A2K8XAU0_9FLAO Unreviewed; 811 AA.
AC A0A2K8XAU0;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CW736_12070 {ECO:0000313|EMBL:AUC80059.1};
OS Nonlabens sp. MB-3u-79.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Nonlabens.
OX NCBI_TaxID=2058134 {ECO:0000313|EMBL:AUC80059.1, ECO:0000313|Proteomes:UP000232401};
RN [1] {ECO:0000313|EMBL:AUC80059.1, ECO:0000313|Proteomes:UP000232401}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB-3u-79 {ECO:0000313|EMBL:AUC80059.1,
RC ECO:0000313|Proteomes:UP000232401};
RA Collins E., Ducluzeau A.-L.;
RT "Pharmacopeia of the Arctic Ocean.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP025116; AUC80059.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8XAU0; -.
DR KEGG; nob:CW736_12070; -.
DR OrthoDB; 9811889at2; -.
DR Proteomes; UP000232401; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 2.10.70.100; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000232401}.
FT DOMAIN 376..428
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 446..663
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 685..800
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 735
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 811 AA; 91909 MW; 85A4F106F4365FC1 CRC64;
MKSNEKPTYK ELEHRINELQ SQIKTKQDYK RLFENASISI WNEDLSLVFE QIEELRKLDI
PNFKIYLENN PEVLGSLIRK LKINSVNKAT LKLFKAGSDQ EFLSNLQSTF GEGANQVFIA
LLESIWNKAK SFTSEVNYKT LDGDEFAALF SIPIPETKLE QQSVPVMIQS IQPLKEAEQA
KEDSLIKLRE AQKLSHVGSW EWKWETDDAV WSDEMYQIYG VKKENFIPTS ENVGKAILEE
DKHKMEQAII QLFKGGVTEP FEFKIARPNN EIRYLSILAL QIYEGTVFGV TQDITDRKKR
ENELNEAQKL AKIGSWLFNP LSKKVEWSDE TFHMWGFDSK KDAAPDADTL IQRIHPDDQE
LWSNSVDKAT QHGIAYDIEI RVCLPNDQQK TIRAICQPIK GVNDKVISLA GTNQDITQQK
LLAMELINAK EKAEESDRLK TAFLANMSHE LRTPMNGILG FAELLKRKNI TVETKDTYLG
FIEKEGNRLL SFISNIVDIS KIESNVITVE KSFCNVNELI DDLYSKYSFR LENTAVQLLI
KKGLDDPHSG VETDANKLIQ VFSNLLENAI KFTKEGVIEF GYSLSKNKLE FYVKDTGIGI
EKEEQKNIFN RFMQGKLEQT HNHGVGLGLS IVKGIVAILG GDVGLESQTG VGSTFFFSIP
YQKAVADTKV VLDTNNTTLD SDHFTILIAE DDRFNFLYLK ACLSEVDCTI LHAVNGKEAV
QLVNENSSID VILMDINMPK MNGYEALEEI RKTNKEMPVI AQTGLAMSGD KEKMLQAGFN
DYISKPISPK VLMSTINKHL IKIAPSKHGI K
//
