ID A0A2K8XDY8_9FLAO Unreviewed; 503 AA.
AC A0A2K8XDY8;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=CW733_02990 {ECO:0000313|EMBL:AUC81151.1};
OS Lacinutrix sp. Bg11-31.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Lacinutrix.
OX NCBI_TaxID=2057808 {ECO:0000313|EMBL:AUC81151.1, ECO:0000313|Proteomes:UP000232662};
RN [1] {ECO:0000313|EMBL:AUC81151.1, ECO:0000313|Proteomes:UP000232662}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bg11-31 {ECO:0000313|EMBL:AUC81151.1,
RC ECO:0000313|Proteomes:UP000232662};
RA Collins E., Ducluzeau A.-L.;
RT "Pharmacopeia of the Arctic Ocean.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP025118; AUC81151.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K8XDY8; -.
DR KEGG; laci:CW733_02990; -.
DR OrthoDB; 9808408at2; -.
DR Proteomes; UP000232662; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43711:SF24; SENSOR HISTIDINE KINASE RPPB; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF13426; PAS_9; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:AUC81151.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000232662};
KW Transferase {ECO:0000313|EMBL:AUC81151.1}.
FT DOMAIN 7..77
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 202..256
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 285..501
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 503 AA; 57678 MW; 161BEDF072CAFF48 CRC64;
MEIFKKTSNV FKTLSEAVSE GIVVVNSRQV IVATNKSSNT LFGYEEDELI GKPLDILIPQ
KYHHNHSKHV ETFLEHSDKR QMGHGRNLYG LRKDGSTFPV EAGLNPFTIY DNDYVMALII
DITVRKKAEE DLKHWANIFN ESLNEIFIFD TQTLKFLNVN AGAIKNIGYS LEELRQLTPI
DIKPNLNEVQ FKDAIQPLLD GTEIKIKFNT IHQRKDGSQY PVEIHLQRSR SSDRDTLIAI
ILDITERVNY TERLEKTVEE RTQQLQEALH VEKELNELKT KFLSLVSHEF KTPLSGILTS
SILIGKYTES EQQKKREKHI NTIQNKVKYL NNIINDFLSI ERLESGKVNY KFSTFSLSKV
VNEVIYDANM LLKEGQTIIY PDAIDDIVLD FDEKILELML TNLINNAIKY SPENTKIEVE
VWVEKEGLKI SIIDFGIGIP EQEQKFLFNR YFRAENALLT QGTGIGLNIV KSHLENLGGN
ITFISKENKG TTFTVTIPVN IIK
//
