ID   A0A2K8XKP7_9FLAO        Unreviewed;       430 AA.
AC   A0A2K8XKP7;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=O-acetylhomoserine aminocarboxypropyltransferase {ECO:0000313|EMBL:AUC83498.1};
DE            EC=2.5.1.49 {ECO:0000313|EMBL:AUC83498.1};
GN   ORFNames=CW733_15720 {ECO:0000313|EMBL:AUC83498.1};
OS   Lacinutrix sp. Bg11-31.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Lacinutrix.
OX   NCBI_TaxID=2057808 {ECO:0000313|EMBL:AUC83498.1, ECO:0000313|Proteomes:UP000232662};
RN   [1] {ECO:0000313|EMBL:AUC83498.1, ECO:0000313|Proteomes:UP000232662}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bg11-31 {ECO:0000313|EMBL:AUC83498.1,
RC   ECO:0000313|Proteomes:UP000232662};
RA   Collins E., Ducluzeau A.-L.;
RT   "Pharmacopeia of the Arctic Ocean.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933,
CC         ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
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DR   EMBL; CP025118; AUC83498.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K8XKP7; -.
DR   KEGG; laci:CW733_15720; -.
DR   OrthoDB; 9803729at2; -.
DR   Proteomes; UP000232662; Chromosome.
DR   GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR   PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR   PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|PIRSR:PIRSR001434-2};
KW   Reference proteome {ECO:0000313|Proteomes:UP000232662};
KW   Transferase {ECO:0000313|EMBL:AUC83498.1}.
FT   MOD_RES         207
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ   SEQUENCE   430 AA;  46009 MW;  B326BF2CDB5A5D56 CRC64;
     MSTQKFATQA LHAGHDTSKT GGTRAVPIYQ TSSYVFDDSD DAAGRFNLSV PGFIYTRLNN
     PTNDILEQRI AALEGGIAAV ATASGTAAIS TTLLTLLKAG DHIVASSSLY GGTYNLLSVT
     LPRHGITTTF VDPSDSENFG KAAQENTRAI FVESLGNPKL DVLDLEAISK EAKAVKVPLI
     VDNTVATPYL LNPIAHGANI VIHSLTKYIN GNGTSLGGII IDAGTFDWTN GKFPEFTEPS
     AGYHGLVYSE AIGAAAFIVK VRIEGLRDYG GALSPFNAFQ IIQGLETLEL RILKHSQNAL
     ELAKWLQEQP EVTWVNYPGL QTSKYNSLAK KYLPKGQSGV VTFGVDGGFE SAKKIADTTK
     LFSLLANIGD TKSLIIHPAS TTHQQLSDEA QKLTGVTKDL IRLSVGIENI EDLKADLKEA
     FIVVKKTVLA
//