ID A0A2K9E5V5_9FIRM Unreviewed; 458 AA.
AC A0A2K9E5V5;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Multidrug resistance protein NorM {ECO:0000313|EMBL:AUG57758.1};
GN Name=norM {ECO:0000313|EMBL:AUG57758.1};
GN ORFNames=HVS_09270 {ECO:0000313|EMBL:AUG57758.1};
OS Acetivibrio saccincola.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Acetivibrio.
OX NCBI_TaxID=1677857 {ECO:0000313|EMBL:AUG57758.1, ECO:0000313|Proteomes:UP000233534};
RN [1] {ECO:0000313|EMBL:AUG57758.1, ECO:0000313|Proteomes:UP000233534}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SR1 {ECO:0000313|Proteomes:UP000233534};
RA Pechtl A., Ruckert C., Koeck D.E., Maus I., Winkler A., Kalinowski J.,
RA Puhler A., Schwarz W.W., Zverlov V.V., Schluter A., Liebl W.;
RT "Complete genome sequence of Herbivorax saccincola GGR1, a novel
RT Cellulosome-producing hydrolytic bacterium in a thermophilic biogas plant,
RT established by Illumina and Nanopore MinION sequencing.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP025197; AUG57758.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K9E5V5; -.
DR KEGG; hsc:HVS_09270; -.
DR Proteomes; UP000233534; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13134; MATE_like_8; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR InterPro; IPR047135; YsiQ.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR42925; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR PANTHER; PTHR42925:SF1; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000233534};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..149
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 319..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 458 AA; 50146 MW; 7CD01657A62ACC56 CRC64;
MMANTKTNNK LTVAALTWPI FIEMLFRIML GNIDTIMLSR YSDNAVAAVG VVNQINSILI
MLYWVVSTGT AVLVSQNLGA KNERKASEVA VTATSSALIY GVVVGALIFA FSEPILRLLN
VPEELMGYAL IYLRITGGFS VAQAMLATLS SIIRSYGHTR ITMYVTMGMN AINVIGNSLF
IFGLFGVPKL GVTGVAISTV AAQILGFSVM LLIIMKNPRM RFNFRYLKPL PVQTIKDILK
IGIPSAGEGA AYHLSQLTIT RIITEMGTVA LTTKVYTNNV MMFIMIFGIA VGQGTQILVG
HLVGAGKKEE AYRTCLKSLR IALLIVFCMS IIIFTFSKNL LGLFTEDQSI IDLGSRLLLL
SIFLEPGRVF NVVIINSLRA AGDVKFPVVM GVFSMWGVAV LLSFVLGITF NLGLIGVWIA
LGCDEWCRGL MMLFRWRSRA WQSMSLTDTS YQLQSSNT
//
