ID A0A2K9EDW8_9FIRM Unreviewed; 321 AA.
AC A0A2K9EDW8;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=dTDP-glucose 4,6-dehydratase {ECO:0000313|EMBL:AUG57405.1, ECO:0000313|EMBL:PQQ67332.1};
DE EC=4.2.1.46 {ECO:0000313|EMBL:AUG57405.1};
GN Name=rffG {ECO:0000313|EMBL:AUG57405.1};
GN ORFNames=B9R14_11615 {ECO:0000313|EMBL:PQQ67332.1}, HVS_07450
GN {ECO:0000313|EMBL:AUG57405.1};
OS Acetivibrio saccincola.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Acetivibrio.
OX NCBI_TaxID=1677857 {ECO:0000313|EMBL:AUG57405.1, ECO:0000313|Proteomes:UP000233534};
RN [1] {ECO:0000313|EMBL:AUG57405.1, ECO:0000313|Proteomes:UP000233534}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GGR1 {ECO:0000313|EMBL:AUG57405.1}, and SR1
RC {ECO:0000313|Proteomes:UP000233534};
RA Pechtl A., Ruckert C., Koeck D.E., Maus I., Winkler A., Kalinowski J.,
RA Puhler A., Schwarz W.W., Zverlov V.V., Schluter A., Liebl W.;
RT "Complete genome sequence of Herbivorax saccincola GGR1, a novel
RT Cellulosome-producing hydrolytic bacterium in a thermophilic biogas plant,
RT established by Illumina and Nanopore MinION sequencing.";
RL Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PQQ67332.1, ECO:0000313|Proteomes:UP000239720}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A7 {ECO:0000313|EMBL:PQQ67332.1,
RC ECO:0000313|Proteomes:UP000239720};
RX PubMed=29482868; DOI=10.1016/j.syapm.2018.01.010;
RA Aikawa S., Baramee S., Sermsathanaswadi J., Thianheng P., Tachaapaikoon C.,
RA Shikata A., Waeonukul R., Pason P., Ratanakhanokchai K., Kosugi A.;
RT "Characterization and high-quality draft genome sequence of Herbivorax
RT saccincola A7, an anaerobic, alkaliphilic, thermophilic, cellulolytic, and
RT xylanolytic bacterium.";
RL Syst. Appl. Microbiol. 41:261-269(2018).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP025197; AUG57405.1; -; Genomic_DNA.
DR EMBL; NEMB01000003; PQQ67332.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K9EDW8; -.
DR KEGG; hsc:HVS_07450; -.
DR OrthoDB; 9811743at2; -.
DR Proteomes; UP000233534; Chromosome.
DR Proteomes; UP000239720; Unassembled WGS sequence.
DR GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43000:SF7; DTDP-D-GLUCOSE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43000; DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED; 1.
DR Pfam; PF16363; GDP_Man_Dehyd; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:AUG57405.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000233534}.
FT DOMAIN 5..306
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF16363"
SQ SEQUENCE 321 AA; 36545 MW; 88F14576FE401342 CRC64;
MRVLLVTGGA GFIGSNFIKF FIRRNKNFLI INMDNLGPSS NLNNLKELER SPRYHFVNGS
ICNQELVNYV IKRHRPDVII NFAAETNVNK SLANPIAFSQ TNVLGTLTLL ESARYFWSKQ
NFKGKLFIQP STYQVYGSTY NDGVFFIEDS NISPQNPYAA SKASADLIVK SSYDSYGFPA
IIARSCQNYG PFQNINEFIP SCIYNILNNT EIPIKKDASV RREWIHVLDN CVALIRILFY
GKVGEIYNIG SGYELSDYEI AQELLRLSGK PYDKTKAENI SRCVLNSYKL KNNLNWGTKF
SLTDGLIDTI HWYKGYFSKS K
//
