ID A0A2K9L9G3_9RHOO Unreviewed; 960 AA.
AC A0A2K9L9G3;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=EAL domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=B4966_04915 {ECO:0000313|EMBL:AUL99587.1};
OS Rhodocyclaceae bacterium.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales;
OC Rhodocyclaceae.
OX NCBI_TaxID=1898103 {ECO:0000313|EMBL:AUL99587.1, ECO:0000313|Proteomes:UP000235024};
RN [1] {ECO:0000313|EMBL:AUL99587.1, ECO:0000313|Proteomes:UP000235024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Thauera-like {ECO:0000313|EMBL:AUL99587.1,
RC ECO:0000313|Proteomes:UP000235024};
RA Umu S.U., Elley S., Stott M., Poole A.M.;
RT "A full genome of an Rhodocyclaceae isolate from Taupo Volcanic zone.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP020026; AUL99587.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K9L9G3; -.
DR KEGG; rbh:B4966_04915; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000235024; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR004010; Double_Cache_2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR033480; sCache_2.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF08269; dCache_2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM01049; Cache_2; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000235024};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 404..474
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 477..530
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 562..700
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 709..960
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 38..65
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 960 AA; 108250 MW; 0F26796E3E75D35E CRC64;
MNLSDKARTV PRIHLIGTLT IVSVLTVLLG SFFAWQNLVD QQKSIERLEE AISRQLVERL
QAEMALALDF VEFTRAGTEA LLRQELVEQV DQAMAIAEGI YRSASGHHPP EVVQRLIVEA
LRPVRFFDGR GYYFIDDMTG RFILLPTAPH LEGRLMPDNQ DDTGHFIMRG LIEAARKPKE
QSFSRYRWYR PDDPQHMADK LAYVRHFPPF DWLIGTGDYI HEWEARQQRA VLTRLRSQRF
GDSGGFSVID RDGRVLLSAE APELEGKRLD DIPPSTAQLL RAFAELADSH QEVLRYEWPD
RSAGATLPRL AFAQNIPEWG WTLIATVAEK ALRDELSRER LDAEEVNGDR LLKFSAVIGI
VLLIAMSASL LFSRWSHRLF RAYHEENAAQ REALRQQAGK LRESEDRLAT ILDSVEAYIY
IKDPQYRYRY ANRRVRELFG RELDAIIGER DESFFDPDTA RQLLENDKQV IEHGKRVAVE
ERSVLRDGGE ARTFLSIKLP LRRDDGEIYA LCGISTDITQ RKRMEDEIRQ LAFYDPLTGL
ANRRLLADRL QQQLLASARS GQYGALLFID LDNFKTLNDT LGHDAGDLLL QQVAHRLGFC
VRQGDTVARF GGDEFVCMLN DLGNSAAAAA AHAKTVGEKI LELLRQPFRI HSRIHVSTPS
IGITVFAGHQ ATVEELLKQA DMAMYQAKTA GRNGLRFFDP QMQARLQERA TLESELRLAL
DAGQLSLYYQ PQVDIDGRIT GVEALLRWTH PQRGPVAPGD FIALAEETGL ILPIGAWVLE
SACEQLRRWS AAPATAGWTV SVNVSALQFQ QADFVDLVID TLARHGANPH RLTLELTESM
VHDIDHTLPR MHALKAHGIR FSLDDFGTGY SSLAYLKRLP LDELKIDRSF VRDLLTDPND
ALIAQTIVSL TRTLGLRVIA EGVETAAQRQ ALIAQGCLHF QGYLFSPPVP AERLTAGLAE
//
