ID A0A2K9LJT9_9GAMM Unreviewed; 983 AA.
AC A0A2K9LJT9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=Kalk_04735 {ECO:0000313|EMBL:AUM11765.1};
OS Ketobacter alkanivorans.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Ketobacteraceae; Ketobacter.
OX NCBI_TaxID=1917421 {ECO:0000313|EMBL:AUM11765.1, ECO:0000313|Proteomes:UP000235116};
RN [1] {ECO:0000313|Proteomes:UP000235116}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GI5 {ECO:0000313|Proteomes:UP000235116};
RA Kim S.-J., Rhee S.-K.;
RT "Direct submision.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP022684; AUM11765.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2K9LJT9; -.
DR KEGG; kak:Kalk_04735; -.
DR OrthoDB; 9787514at2; -.
DR Proteomes; UP000235116; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 2.60.40.2380; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011622; 7TMR_DISM_rcpt_extracell_dom2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF07696; 7TMR-DISMED2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000235116};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..983
FT /note="Diguanylate cyclase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014772261"
FT TRANSMEM 200..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 421..458
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 496..549
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 581..714
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 725..980
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 983 AA; 111052 MW; 46DFDA3FBAEB8489 CRC64;
MTCNRHSNPL TLKATLACLV VSVFSLFATV LQAATGFSGV SHVAANQQDD PLDLSISVLV
DGSGRLLIDD LLTSRLGQEW SPLTEPSLNL GFVQSTIWLS ASIPNFARGS DYLLVVDFPL
LDELDVFFVS GEQVVSHVIT GDQRPFMQRP FWHRDYVLAL PDEQFEDLRV ILRVRSEGSV
LVPVRLWRQD AFWAQEQSTL LLKGGFIGIM LVMVLYNLFI YVVVRDQSYL YYVGYGVSIL
LFQLSIEGLA YQYLWPQLKE WHQISLILFL AFSVVFHCMF TLTFLNLPKR LPAASYALAL
LISVALLLSS LSVVLSYNVS IQLVTFLVLP TLITCMSVGV YLLYKGERRA RYFVGGWFVY
FFGAFVLTLT RMGWIPVNEL TEYMLQIGVA LEVVLFSMAL ADSINIERRE KLEAQRQSIQ
NLERYRSLYE NAAEGIYQSD LDGRLISVNP SLASMLGYAN PAELMTAFSQ KEITEFLNEV
DYNSLIRNIM EKGRVHQFEL RGLRRDGQVC WLSVSAKVVA GAQWGNDAMV EGFVSDITQR
KRNEEQLMFL SRHDPLTGLV NRREFESRLH QALEEVHHQS EHHTLLLLDL DQFKLINDTC
GHVAGDELLR QVTVLLRQLT RGGDVLARLG GDEFGILLTN CAEDNAIMVA QKIRHQIQSM
RFEWDGSMFN MAGSVGLVTI KREMDSVKEV INLADAACHT AKNSGRNRVH VYDPEDVHLA
SHQTHMQWAA RISDAIEHDS FMLYVQPIVA VTADPFVGKS YEVLLRLNYD NGIVYPGTFL
PAAERYNLMP QVDRWVVQNL FKWMENNPKK LSGVADVSVN LSGLTLGDNE FPAFLREQFE
RYGIAPNKIC FEITETIAVT NLSTTLKFIE EFRAIGCSFS LDDFGSGFSS YGYLKSLPVD
YLKIDGVFVK DMVASDIDCA MVESINRIGH VMGKKTIAEF VESEEITDML RRMGVDYAQG
YGISKPYPID DIEVFIPATP RHP
//
