ID   A0A2K9P3A4_9FIRM        Unreviewed;       823 AA.
AC   A0A2K9P3A4;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=MMPL domain protein {ECO:0000313|EMBL:AUO19711.1};
GN   ORFNames=B9O19_01553 {ECO:0000313|EMBL:AUO19711.1};
OS   Monoglobus pectinilyticus.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Monoglobus.
OX   NCBI_TaxID=1981510 {ECO:0000313|EMBL:AUO19711.1, ECO:0000313|Proteomes:UP000235589};
RN   [1] {ECO:0000313|EMBL:AUO19711.1, ECO:0000313|Proteomes:UP000235589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=14 {ECO:0000313|EMBL:AUO19711.1,
RC   ECO:0000313|Proteomes:UP000235589};
RA   Kim C., Rosendale D.I., Kelly W.J., Tannock G.W., Patchett M.L.,
RA   Jordens J.Z.;
RT   "Monoglobus pectinilyticus 14 draft genome.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR   EMBL; CP020991; AUO19711.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2K9P3A4; -.
DR   OrthoDB; 9782006at2; -.
DR   Proteomes; UP000235589; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000235589};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        40..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        309..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        363..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        657..677
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        698..720
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        740..762
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          170..338
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
FT   DOMAIN          553..770
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
SQ   SEQUENCE   823 AA;  91569 MW;  1B11669895DE153B CRC64;
     MQAAEYNIVK SRFEWSDTVK NSDENIMEKV ALFIVDKRKA FYLLFAIAFV FCAICIPKVQ
     VENDISAYLP ESTETKQGLD LMDREFVTHD TFSLMISNIP YNQAEKMTDK IEEVGGVKEV
     EFDDSEDHYK NSSAIYTVTL DSGLDNEREI EIENEVKNKF AEYDCYTYSA SIDNSSDSLA
     ADMRQIIMYV AIIIVLMLLF TSKSFMDVAV FLIVFIVAAV LNMGTNYLLG TISFISNSVA
     IVLQLALAID YAIILSHRFA EEKQTKNSHD AIVAALSKAI IEISSSSLTT VAGLAALMTM
     QLGIGKDLGL VLCKGIICSL ITVFLLMPGL LYMFSNAIDK TVHKNYVPDI SFWGKIVMKT
     RSFVPIIFAL VIVSSIFLSS MCQYAFDQDS VSSPRLSDSK KAENKIKENF DVGGQLAVIV
     PKGSYDKEKK ILQDVEEYDG ISTALGLANV EVDDDYCLTD KVTPRQFADL MSLDIATSRV
     LFQAYGASVS QYTPIFQDVD SYTVSIMDIL MFVHEQMDYG VIDLGEEKNS DINEVYDKVS
     DARDQLEGEE YSRLVFTYKG KNESEEVIAL HDKVREEAKR YYDDPILVSN AISALDLKSS
     FSGDNQKINL FTIISVLLIL LATFKSSSVP VLLVLTIQGS IWINFSFPYL MNEKLYFLGY
     LVVSSIQMGA TIDYAIVFTN RYLELKPEIG KKAAAIEAIN GAFPTILTSG LIMMIAGFLI
     GFISTNPVIS ALGKCLGRGT LISIILVMTL LPQIMVLFDK LVEKGAFTLK KKEKKERTGI
     VYVDGRVKGY INGYVNGTIH GMVKGDVKAI VENMSGPEDE QKQ
//