ID   A0A2L0A9E6_9SPHN        Unreviewed;       334 AA.
AC   A0A2L0A9E6;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   SubName: Full=Alpha-ketoacid dehydrogenase subunit beta {ECO:0000313|EMBL:AUW58417.1};
GN   ORFNames=C1T17_10200 {ECO:0000313|EMBL:AUW58417.1};
OS   Sphingobium sp. SCG-1.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=2072936 {ECO:0000313|EMBL:AUW58417.1, ECO:0000313|Proteomes:UP000239825};
RN   [1] {ECO:0000313|EMBL:AUW58417.1, ECO:0000313|Proteomes:UP000239825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCG-1 {ECO:0000313|EMBL:AUW58417.1,
RC   ECO:0000313|Proteomes:UP000239825};
RA   Tavormina P.L.;
RT   "Members of Methylobacter and Sphingobium form part of a microbial response
RT   to natural gas loading in southern Californian soils.";
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR   EMBL; CP026372; AUW58417.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2L0A9E6; -.
DR   OrthoDB; 7821727at2; -.
DR   Proteomes; UP000239825; Chromosome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000239825}.
FT   DOMAIN          1..176
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   334 AA;  36564 MW;  49F813451D338F2F CRC64;
     MNMIQAINSA LDVMMDRDPH VVVMGEDVGY FGGVFRATAG LQKKYGKNRV FDTPITECGI
     IGVAVGMGAY GLRPVPEIQF ADYIYPALDQ LVSEAARLRY RSAGEFIAPM TVRSPFGGGI
     FGGQTHSQSP EGIFTHVSGI KTVIPATPYD AKGLLIAAIE DNDPTIFFEP KRIYNGPFDG
     HYDRPSRNWG GHADAQVPEG YYKIPLGKAR IARAGEALTI LCYGTMVHVV ASTVEEMGVD
     AEIIDLRTLV PLDIEAIEAS VKKTGHCLIV HEATRTSGFG AELSALVQER CFYHLEAPIE
     RVTGFDTPYP HSLEWAYFPG PIRIRDAINK ILKD
//