ID A0A2L0AFQ2_9SPHN Unreviewed; 756 AA.
AC A0A2L0AFQ2;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=C1T17_20685 {ECO:0000313|EMBL:AUW60624.1};
OS Sphingobium sp. SCG-1.
OG Plasmid unnamed {ECO:0000313|EMBL:AUW60624.1}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=2072936 {ECO:0000313|EMBL:AUW60624.1, ECO:0000313|Proteomes:UP000239825};
RN [1] {ECO:0000313|EMBL:AUW60624.1, ECO:0000313|Proteomes:UP000239825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCG-1 {ECO:0000313|EMBL:AUW60624.1,
RC ECO:0000313|Proteomes:UP000239825};
RC PLASMID=Plasmid unnamed {ECO:0000313|Proteomes:UP000239825};
RA Tavormina P.L.;
RT "Members of Methylobacter and Sphingobium form part of a microbial response
RT to natural gas loading in southern Californian soils.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP026373; AUW60624.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2L0AFQ2; -.
DR OrthoDB; 9764438at2; -.
DR Proteomes; UP000239825; Plasmid unnamed.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00156; REC; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; NF041832; near_NosP_CTERM; 1.
DR PANTHER; PTHR43047:SF9; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12860; PAS_7; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AUW60624.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Plasmid {ECO:0000313|EMBL:AUW60624.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000239825};
KW Transferase {ECO:0000313|EMBL:AUW60624.1}.
FT DOMAIN 400..611
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 632..750
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT COILED 202..229
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 684
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 756 AA; 83145 MW; 6CF5E3743298FFE7 CRC64;
MTKTFESLGR HANGSAEYEL QKLRRINTAL INRVERATDL QGNAFSLFET AITLESRVRD
RTVELERTLS ELAAASASSL QARSIAEDAQ RRLRDAIDTI NEGFALFDQN DRLVLCNQTY
LGLWPRIADR IHAGMAFSEI AQMIVTDGTT LGAMVAPDRW VSERSRQHAV AAGGHVHALA
DGRWIQINER RTSDGGIVCL YTDITEAKAE DARQRAQELA EKSTLLQATL DNIPQGVCVF
GPTGELVAWN GSLRALLDLP ADVADAIATH GRFLSLWNVR RADIGENDCV EWLGSEEKER
IVQRSLSDGR SLEIRRARMP DGGLMITFSD ISESRRAATV LLEANDSLER RVAERTSEMA
AVNSKLQREI AERLGVEAAL REAKGLAEQA NLSKTRFLAA ASHDLLQPLN AARLFVSALE
DRRMALASRA LINQTSSALE SVEYLLEALM EISKLDAGAV VPELREFPIG DLLRNMKAEF
LPLARAGGLE LRISDCGTWV RSDARLLRRV LQNFISNAIK YTKTGTVSVE WTIRGDVVRL
SVTDTGPGIP AEHHVEVFQE FFRLDGGAPN RGMGLGLAIV QRASRMLDHP VHLESKQGVG
STFSIDVPTT TAQATSIAIP ALAKRRDLSA LRILVIDNDI SILSAMTALL SGWGCEVLTA
RAADEAVSYL RSHDAILPHL ILADYHLDCD ALGDDAVRLF RSEANAQIAA IIITADRSPD
LRQHLMRNGF HVLTKPLKPA QLRAMLSRTV EDLHLP
//
