ID A0A2L0ET04_SORCE Unreviewed; 555 AA.
AC A0A2L0ET04;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=site-specific DNA-methyltransferase (adenine-specific) {ECO:0000256|ARBA:ARBA00011900};
DE EC=2.1.1.72 {ECO:0000256|ARBA:ARBA00011900};
GN ORFNames=SOCE26_038680 {ECO:0000313|EMBL:AUX42436.1};
OS Sorangium cellulosum (Polyangium cellulosum).
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=56 {ECO:0000313|EMBL:AUX42436.1, ECO:0000313|Proteomes:UP000238348};
RN [1] {ECO:0000313|EMBL:AUX42436.1, ECO:0000313|Proteomes:UP000238348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So ce26 {ECO:0000313|EMBL:AUX42436.1,
RC ECO:0000313|Proteomes:UP000238348};
RA Zaburannyi N., Bunk B., Overmann J., Mueller R.;
RT "Sorangium comparison.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an
CC N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-
CC homocysteine; Xref=Rhea:RHEA:15197, Rhea:RHEA-COMP:12418, Rhea:RHEA-
CC COMP:12419, ChEBI:CHEBI:15378, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:90615, ChEBI:CHEBI:90616; EC=2.1.1.72;
CC Evidence={ECO:0000256|ARBA:ARBA00001279};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP012673; AUX42436.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2L0ET04; -.
DR REBASE; 232795; M.Sce26ORF38680P.
DR OrthoDB; 9784823at2; -.
DR Proteomes; UP000238348; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0009007; F:site-specific DNA-methyltransferase (adenine-specific) activity; IEA:UniProtKB-EC.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR33841; DNA METHYLTRANSFERASE YEEA-RELATED; 1.
DR PANTHER; PTHR33841:SF5; TYPE II METHYLTRANSFERASE M.HINDII; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 13..209
FT /note="DNA methylase adenine-specific"
FT /evidence="ECO:0000259|Pfam:PF02384"
SQ SEQUENCE 555 AA; 60897 MW; 0AB0C7816A5AD732 CRC64;
MGTQLALLFD NSRTRKARGA FFTPSELATF LASWAVRTPK DRILEPSCGE ASLLLAAGRQ
LLARGGRTTL VGLDVHEPSI AAAKQLLRDE KLRADLRVAD FFDEAPEPRF DVVIGNPPYI
RYQSFSGKDR AKAQRAALAQ GVRLSGLANA WAAFVVHAAS FLRKGGRLAL VLPASLLSVN
YAAPVRRFLL DRFKAVKLVM FEERVFPDVL EEVVLLLAEG EGPTSRFDLL QVRDLEELGS
IQGPSGASPR PWTPIDADDK WTEALLPSGA AGIYSELASG VGFKTLGDWG DTDLGMVTGN
NQFFTLTATQ VAELGLRESE TVRISPPGSR HLRGLVFSDR TFDEMAREGS RVYLFYPDKD
RPSKAAKRYI ELGESQGIHK AYKCAVRSPW WRVPTVRIAD LFLTYMNHDV PRLVHNNASV
AHLNSIHGVT LSRGNRELGA DLLPIAMLNS LTMLGAELVG RSYGGGILKV EPKEADLLPM
PSPEVLEIVG PDLRNLRSQL SRLLRNSQLA EVVRSVDEAL LVGGLKRSRE DVVALSEARN
MMAARRSSRA GKTPR
//
