ID A0A2L0F7V4_SORCE Unreviewed; 1857 AA.
AC A0A2L0F7V4;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SOCE26_091880 {ECO:0000313|EMBL:AUX47666.1};
OS Sorangium cellulosum (Polyangium cellulosum).
OC Bacteria; Myxococcota; Polyangia; Polyangiales; Polyangiaceae; Sorangium.
OX NCBI_TaxID=56 {ECO:0000313|EMBL:AUX47666.1, ECO:0000313|Proteomes:UP000238348};
RN [1] {ECO:0000313|EMBL:AUX47666.1, ECO:0000313|Proteomes:UP000238348}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=So ce26 {ECO:0000313|EMBL:AUX47666.1,
RC ECO:0000313|Proteomes:UP000238348};
RA Zaburannyi N., Bunk B., Overmann J., Mueller R.;
RT "Sorangium comparison.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP012673; AUX47666.1; -; Genomic_DNA.
DR OrthoDB; 5342108at2; -.
DR Proteomes; UP000238348; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd00130; PAS; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR011102; Sig_transdc_His_kinase_HWE.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF07536; HWE_HK; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00911; HWE_HK; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AUX47666.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AUX47666.1}.
FT DOMAIN 56..325
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1538..1611
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 1613..1662
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1514..1548
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 22..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1857 AA; 206162 MW; 624B542782FAF088 CRC64;
MLDASRLGAR CAGGGPRPPA AGRGREVERR RGASDAKDLP MTPAPMPPGT LQINGYHVIA
KTGEGAGYAA YQARREADGV EVAIKVLYTA YADYADYADC ARMSDVMRCK HAYRVIQRID
SARVVKVYAV EEHGDGLALV TEVFPGPPLS ARTRRKLDVC ALLDTMIPVA EALADIHRHG
LVHGDVRPPN ILLGEGGQVK LTGFGVDSLV TREKEEIYCP RVLSEVLPYT SPEQTGRMNR
SVDYRTDMYS LGVVLFEVLV GRRPFEAMDP LELIHAHIAV EPVPPAEIDP EVPAALSAVT
TKLLSKNAED RYQCAEGLKA DLEEIRSRRR SRGQIGAFRP GQYDRRDLFR LHQKLYGREG
DIQELVGSFD DVLRGKRTTV LVSGYSGIGK SSLVQEILKP LAREKGYYIS GKYDQYNRDT
PYSAIVQAFD ALVRQLLFES EERITTWREG ILSALGSNGQ VLCDVLPSLK HIIGEQPPVP
ALGPVEAQNR FILYFQNFVS VFARHAHPLA MFLDDLQWVD SASLSLIASI LAKENVEALF
FCGAYRDNEV SPTHPFLAAL EELAEGGLEV RNIVLEPLRL THLVELINDS LQIRDGGALA
GAVLKKTGGN PFFVKQFMRH LYDAKLLVFD PATGWRWDLP QIERLECTDN VVSLMADTIR
RLPQATQRVL RLASVIGNTF ELDVLNTVSE RPPDETYGCL DGALGEGLIV SAGEQYRFAH
DKIQEAAYSL IPERDRPAFH YRIGELLLGK LRSDRGHNLF DVVNHLNSAG ALIQDPQERM
ESARLNLLAS GRAEESTAFT AALKYLEHGM AMLPEDAWIS NYELAFTYHT KKGLMESLCG
RHDDALSTLG ASFDKARGRL HRTEVRRLKM NVEILKNDLP AAMEEGLAAL RAYDIDLPPY
PDDGALNAEL ERTIAVIGGR PIASLVDLPA LNDPEIAALQ DVLQEMFSPT YQLGTNNFGI
TVMKALQNSL RHGLSKSSIY AYVNFGTFLC ARLDIEKGYE FGRAAVRLNE RHPDAKSESM
LCNMWGAWVQ HWMDTYETSK ASLRKGVHAG IETGQYIWAF YNACNATMNR LLRGAHLHDV
IEEARQHAPL CKLDKFNTIT WMVGAVAQLC EQLGAPDGGD WARGAWVDIH AVAEEARTIN
NQASLYFLNV FRVLAGVFDG AYEDVAELWG STDPGSLGML AAWHASPCYY FYGGLASSRA
AGTAAPALRE VYLARLRECA RKVESWAALG PQSHRHRCLI LNAELARSEQ REDVGALYDQ
GITAAREGQF LHDAALANEL CARHYLDRGR AFVACAYMTE AHRLYARWGA ARPMRRIERN
FPHVLRPEAL RRHAAPMRGG HAEVEGAPHA ELDVTTVLRA SQAVSSELIL DRLIETLLKI
GVEHAGAERG LLICPCGAEH DIEAEVVTRR GRVEVTLRQA PITPADLPTS ILQYVVRTRE
SVILDDATLP NLFSEDAYVR GRRPRSVLCL ALVKQGTLVG VLYLENNLTP RAFTADRIAM
LELLASQSAV SLENARLYTQ LERENSERKR AELALREREA RIRRLVDANI IGIAFWDLDG
RIIDANDAFL SMLRYSRQDL AAEKIYWTES TPTEFREITE GALDEIALTG EFRPFEKEFL
RKDGSRVPVL LGGARFEGSD DQGVAFVLDV TERKEAEERQ KLLLNELNHR VKNTLAIVHA
IAVQTLRMAD SPGAFTEALL ARLLALSQTH NLLNQTSWQG AGLHDVVCAE LAPHADGGAD
RVRLAGQAVR LRPEAAVTLG MVFHELATNA AKYGALSQPS GRVAVTWNVS TQAHEPLLRL
EWQEANGPPV RPPRRKGFGS RLIERDLQRQ LGREVRIEFL PEGVRCVMHL PLDRVAL
//
