ID A0A2L2SUA2_9HYPO Unreviewed; 1372 AA.
AC A0A2L2SUA2;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Histidine kinase {ECO:0008006|Google:ProtNLM};
OS Fusarium venenatum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=56646 {ECO:0000313|EMBL:CEI60992.1, ECO:0000313|Proteomes:UP000245910};
RN [1] {ECO:0000313|Proteomes:UP000245910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A3/5 {ECO:0000313|Proteomes:UP000245910};
RA King R.;
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN649230; CEI60992.1; -; Genomic_DNA.
DR STRING; 56646.A0A2L2SUA2; -.
DR OrthoDB; 1222064at2759; -.
DR Proteomes; UP000245910; Chromosome ii.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43719; TWO-COMPONENT HISTIDINE KINASE; 1.
DR PANTHER; PTHR43719:SF30; TWO-COMPONENT SYSTEM RESPONSE REGULATOR; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000245910};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 559..629
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 863..1156
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1209..1359
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 120..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 895..915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1284
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1372 AA; 152461 MW; 38083B73674774DC CRC64;
MPPSALHNLG LVDLVASDPR PTFVVALPEQ ASCTHDSSAK ILYRNPALQN LHTLDQSISF
IPQDASHSPF WNWVTSPPPA PASEGDAAGP AMTNTQHSLP YLGVFWTRSI VLSQWVVMSG
NETPPSSEPP RKVRIEGKQG EETRKYPQKS PLDNARLPSR KKSESKTPMV YRDESNPGLM
VPVSDSEAEP FLDVVQSVDW ESTSLGPMAD WPAQLQYTFN QLVSDSRPVA LYWGPEYITI
YNEAFSKYCG ARHPELLGQP ATEAWPQLKT RLDEMTASPM KNYSNAEDES KFFIPQADGA
FEETYAKSSM VPIVYEQNCL GIQHSLLEMT SKRLWERRMK MLLDLGEALV STKDAKSYWS
RMIEELERWN PAYDVPLAFI YSVEESDVDS TSSKYDCSKT CRLEGSLGVP LGHAIAPSVL
KLKDTDDGMA SILRRSLDER QPVLLQTKDG TLPKDLLRGL EWRGFGDPCQ AAVVLPVRPT
KEEHVMGVLF LGLNPRRPYD NDYRQFILLL NQKLTSSLAS AVLLEEEARR RRNITEQAAY
DNAMLTQRLE YQTKQAERST KTFTAVAEFI PVGMCFVDNQ GNITFANDAW HRITGYPKGP
IAQGALLESV LEEDKEKVMQ AYKDVQKLDT VTFEYRIART ENTTEPPSFR SSAGPLPVMD
EGVSRHILAS TKAERAPDGS VIRILTCLTD VTVQKDTAEE AVRRAQEAEN LKRLAEFATV
GMYDVSMDGR LLSANNLFWE LTALEKVDLT KVDVRPWPEC VVEEDLYILQ ESLDKLVESG
RTETAEFRLR NGWVSEDGNG NSSVAPRWVL ATFMPVKSSD GVIQSFTGCL SDVSVQKWQL
EQEKLRKEEA IESKRQQENF IDMTSHEMRN PLSAILHCTD AIIASLARVQ DISDNSAPLT
PTRNGTSGEG RRIGERSVEE RKLLEDSIEN AETIVTCAQH QKRIVDDILT MSKLDSKLLA
VTPCTVDPIQ IVNGALKMFE VEARRVDIEL TSYVDKSYKD LAYDYLDLDP SRVQQVLINL
LTNALKFTKS GTTRNVTLGV KGSLTPPGED MTAVQFIPRF CDVSEEYDQP ALKERTKAVY
LLFEVKDTGQ GLTAEEMGSL FNKFVQASAK THTKYGGSGL GLFISRRLTE LQNGAIGVLS
QPGVGSTFAF YIEAYVPSEA SRNEALAAAA AARLITGGSD ADSADGKQNC RDIRLQKHQN
PGGNVRLDGI LVVEDNLINQ QITRRGLTDR GFMADVANHG VEALEILRRR QSTVPGLGLN
GVPGRSGRSH THSLPIAINL VLMDIEMPVQ DGLTCTRIIR ELEAEGEIFC ASGGRMPIIA
VTANARPEQV MEAKQAGCDD VMVKPYRIPE LIEKMQVVVR RMGGLSPNSP VR
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