ID A0A2L2T6E3_9HYPO Unreviewed; 392 AA.
AC A0A2L2T6E3;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
OS Fusarium venenatum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=56646 {ECO:0000313|EMBL:CEI65249.1, ECO:0000313|Proteomes:UP000245910};
RN [1] {ECO:0000313|Proteomes:UP000245910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A3/5 {ECO:0000313|Proteomes:UP000245910};
RA King R.;
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
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DR EMBL; LN649229; CEI65249.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2L2T6E3; -.
DR STRING; 56646.A0A2L2T6E3; -.
DR OrthoDB; 3280806at2759; -.
DR Proteomes; UP000245910; Chromosome i.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd09280; RNase_HI_eukaryote_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.40.970.10; Ribonuclease H1, N-terminal domain; 2.
DR InterPro; IPR009027; Ribosomal_bL9/RNase_H1_N.
DR InterPro; IPR011320; RNase_H1_N.
DR InterPro; IPR037056; RNase_H1_N_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF01693; Cauli_VI; 2.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF55658; L9 N-domain-like; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000245910}.
FT DOMAIN 237..387
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 147..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 392 AA; 43178 MW; 0953DACECE469E1B CRC64;
MKRKAPSGGF GGGSARKKGK KNFYAVKVGR TPGIYHTWDE CSEQVNRFPG AVFQGFVTAE
EAREYMGGSG APSASVPTAR TPSASVTNAS GSMKYYAVAV GSQPGIYNTW GETSRRIQGV
SGAKHKMFDT LGEAEDYIRQ FGAPETCQSL GIAPGPGQQA RQSQQEPRQT PAEQTWEPRS
TAYEPQQKQY QSAAEARPAA RQFQQTQYAS AAEQVEAERD ARKAQHEQKL KKERQAEQDT
IRIYTDGSSL GNGQAGSRAG LGVFFGHDDE RNHAERLPGL PQTNQRAELL AILRAMEIAP
LTQGIEIWTD SQYSINCVQV WSVNWERNNW MTSQKKPVAN KDIVRDIRAK MRERQAAGAV
TKFQWVKGHA SDPGNHEADR LANIGSRMPE VA
//
