ID A0A2M6UZ06_9BURK Unreviewed; 576 AA.
AC A0A2M6UZ06;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Choline dehydrogenase {ECO:0000313|EMBL:PIT71377.1};
GN ORFNames=B9Z42_15680 {ECO:0000313|EMBL:PIT71377.1};
OS Limnohabitans sp. B9-3.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Limnohabitans.
OX NCBI_TaxID=1100707 {ECO:0000313|EMBL:PIT71377.1, ECO:0000313|Proteomes:UP000228506};
RN [1] {ECO:0000313|EMBL:PIT71377.1, ECO:0000313|Proteomes:UP000228506}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B9-3 {ECO:0000313|EMBL:PIT71377.1,
RC ECO:0000313|Proteomes:UP000228506};
RA Kasalicky V., Mehrshad M., Andrei S.-A., Salcher M., Kratochvilova H.,
RA Simek K., Ghai R.;
RT "Unexpected and diverse lifestyles within the genus Limnohabitans.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIT71377.1}.
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DR EMBL; NESI01000012; PIT71377.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M6UZ06; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000228506; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Reference proteome {ECO:0000313|Proteomes:UP000228506}.
FT DOMAIN 286..300
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 85
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 246
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 576 AA; 63009 MW; A60BA4118EDD1A55 CRC64;
MSDTQFDYII VGAGTAGCLL ANRLSANASK RVLLVEAGRK DDYHWIHIPV GYLYCIGNPR
TDWLFNTAPD AGLNGRSLRY PRGKVLGGCS SINGMIYMRG QARDYDQWAD ITGDARWRWD
NSLPYFKLHE DHHAGANALH GAKGARSDVL VGDTTVYGET LRHHIAGGEW RVEKQRLRWD
VLDAFAQAAV QAGIPATDDF NRGSNEGVGY FEVNQKSGWR WNTAKAFLRP MCYARPNFEL
WTNAQVAQLL MTTEADGTQR CTGAKVWTGQ EFVNVTAKES VVLCAGAIGT PQILQLSGLG
PADLLKQHGI EPVIDLPGVG ANLQDHLQIR SVFKVQGVKT LNTLANSWWG KAMIGMEYAF
KRSGPMSMAP SQLGAFTRSS PDQPYPNIEY HVQPLSLDAF GEPLHNFPAF TASVCNLNPT
SRGTVNITSA NFADAPKIAP NYLSTPEDRK VAADSLRVTR RIAAQPALAK YKPEEFKPGV
QYQSDDDLAR LAGDIATTIF HPVGTARMGR LDDAMAVVDP ELRVRDGRGG LVRGLRVVDA
SVMPTITSGN TNSPTLMLAE KAAQWLVHDA LLSTQT
//
