ID   A0A2M6V9L9_9BURK        Unreviewed;      1181 AA.
AC   A0A2M6V9L9;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Indolepyruvate ferredoxin oxidoreductase {ECO:0000313|EMBL:PIT75129.1};
GN   ORFNames=B9Z41_11935 {ECO:0000313|EMBL:PIT75129.1};
OS   Limnohabitans sp. JirII-31.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Limnohabitans.
OX   NCBI_TaxID=1977908 {ECO:0000313|EMBL:PIT75129.1, ECO:0000313|Proteomes:UP000228925};
RN   [1] {ECO:0000313|EMBL:PIT75129.1, ECO:0000313|Proteomes:UP000228925}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JirII-31 {ECO:0000313|EMBL:PIT75129.1,
RC   ECO:0000313|Proteomes:UP000228925};
RA   Kasalicky V., Mehrshad M., Andrei S.-A., Salcher M., Kratochvilova H.,
RA   Simek K., Ghai R.;
RT   "Unexpected and diverse lifestyles within the genus Limnohabitans.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIT75129.1}.
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DR   EMBL; NESA01000009; PIT75129.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M6V9L9; -.
DR   OrthoDB; 9803617at2; -.
DR   Proteomes; UP000228925; Unassembled WGS sequence.
DR   GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   CDD; cd02008; TPP_IOR_alpha; 1.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR046667; DUF6537.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   Pfam; PF20169; DUF6537; 1.
DR   Pfam; PF01558; POR; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Pyruvate {ECO:0000313|EMBL:PIT75129.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000228925}.
FT   DOMAIN          483..573
FT                   /note="Thiamine pyrophosphate enzyme TPP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02775"
FT   DOMAIN          758..944
FT                   /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01558"
FT   DOMAIN          972..1169
FT                   /note="DUF6537"
FT                   /evidence="ECO:0000259|Pfam:PF20169"
SQ   SEQUENCE   1181 AA;  128996 MW;  3CF416F73612852E CRC64;
     MNAPLPEHIR RALDSVTLDD KYSLDVGRAF MSGVQALVKL PMLQRQRDAL QGKNTAGFIS
     GYRGSPLGGY DQALWKAKSY LQAQHIVFQP GVNEELAATA LWGTQQLGFA PPGSNKFDGV
     FGIWYGKGPG VDRCADVFKH ANMAGTTAWG GVLAVAGDDH VAKSSTAAHQ SDHIFKACGT
     PVFFPSSVQD ILDLGLHAIA MSRFSGLWSG MKTIQEIVES SATAVIDPAR VNIVLPEFEM
     PPGGLHIRWP DDALSQEARL FDYKWYAALA YVRANRLNYN AIEGPNDRFG LIASGKAYND
     TRQALLDLGL DDATCQRVGI RLHKVSVVWP LDAQLTREFA TGLQEILVVE EKRQVIEYQL
     KEELYNWRAD VRPHVLGKFN EVEGDFSGGE WSQPNPSANT LLRANADLNP ALIAKAIAQR
     LKKLGLDADT QARVDAQLAI LSAKERAMQV VEVKADRQPW FCSGCPHNTS TRVPEGSRAM
     AGIGCHFMVL WMDRSTSGFT QMGGEGTPWV GQQPFVNDTH MFANMGDGTY FHSGILAIRQ
     SIAAGVNITY KILYNDAVAM TGGQPVGERP EGHSVLQIAH SMKAEGAQRI VVVTDEPDKY
     DGADLGAGVA VFHRDELDRV QREMREIKGC TIIIYDQTCA TEKRRRRKRG TMVDPAVRVV
     INDLVCEGCG DCGVQSNCLS VEPLETEWGR KRTINQSTCN KDTSCLKGFC PSFVTVEGGQ
     LKKKAKGVTA LAYPNPELPE PNLPPLDHAW GMVVAGVGGT GVITIGQLLG MAAHIEGKGI
     VTQDAAGLAQ KGGATWSHVL IANDQDAIRT TRVSLASADL ILGCDPIVTA GKETLQRMRA
     GRTHVALNAY STPTAAFVKN TDWQNPAEQC VAEIAHTVGA EGLSVFDANR VALQTLGDSI
     FVNPMILGYA WQKGWVPLGH EALMRAMELN DVAVAQNQTA FEWGRQCAHD WAAVQTALAP
     SQTVQFHKPA GVDDVIARRV AFLTDYQNAA YAASYLGAVE RVRAAEAALH KTSLTEAVSR
     NLFKLMAYKD EYEVARLHTD AAFLQKIKGM FEGDYTLNYH LAPPLIAKTN AKGELQKQKF
     GPAMLTGFKL LQHFKVLRGT PLDIFGYSEE RRTERVLIDE YRATLDTVLA KLTPDNHALA
     LELARVPEQI KGFGHVKARN LAAARSKWDG LLTQWHAQAL V
//