ID   A0A2M6VAC1_9BURK        Unreviewed;       525 AA.
AC   A0A2M6VAC1;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Deoxyribodipyrimidine photolyase {ECO:0000313|EMBL:PIT75380.1};
GN   ORFNames=B9Z42_08490 {ECO:0000313|EMBL:PIT75380.1};
OS   Limnohabitans sp. B9-3.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Limnohabitans.
OX   NCBI_TaxID=1100707 {ECO:0000313|EMBL:PIT75380.1, ECO:0000313|Proteomes:UP000228506};
RN   [1] {ECO:0000313|EMBL:PIT75380.1, ECO:0000313|Proteomes:UP000228506}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B9-3 {ECO:0000313|EMBL:PIT75380.1,
RC   ECO:0000313|Proteomes:UP000228506};
RA   Kasalicky V., Mehrshad M., Andrei S.-A., Salcher M., Kratochvilova H.,
RA   Simek K., Ghai R.;
RT   "Unexpected and diverse lifestyles within the genus Limnohabitans.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate;
CC         Xref=ChEBI:CHEBI:15636; Evidence={ECO:0000256|ARBA:ARBA00001932};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC       Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PIT75380.1}.
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DR   EMBL; NESI01000004; PIT75380.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M6VAC1; -.
DR   OrthoDB; 9772484at2; -.
DR   Proteomes; UP000228506; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.80; -; 1.
DR   Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR   InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR   InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR   InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR   InterPro; IPR006050; DNA_photolyase_N.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR   PANTHER; PTHR11455:SF9; CRYPTOCHROME-1; 1.
DR   Pfam; PF00875; DNA_photolyase; 1.
DR   Pfam; PF03441; FAD_binding_7; 1.
DR   SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR   SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR   PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE   4: Predicted;
KW   FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW   1}; Lyase {ECO:0000313|EMBL:PIT75380.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000228506}.
FT   DOMAIN          2..131
FT                   /note="Photolyase/cryptochrome alpha/beta"
FT                   /evidence="ECO:0000259|PROSITE:PS51645"
FT   REGION          480..515
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        489..515
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         213
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT   BINDING         269
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
SQ   SEQUENCE   525 AA;  59853 MW;  9EAE84CED89784FD CRC64;
     MSYALVWFKR DLRWQDHAAL ANAAQQGPVR CIYVVEPELW LQPDAALQHF EFVRESLQAL
     DAELRLQGGC VEVHTGELPE VLSRIWQEAP FRTLHAHQET GNGFTYARDL QVGAWCKAHG
     VGWHETPQFG VVRGLRNRNL WQPAWERHMA EPVRDVGALQ FWQCQTLSRA GCTPSQMQAP
     AHLQHNPPLR QRGGRPLALA TLHSFLHARS LGYRGGISSP LSAPDACSRL SAYLAWGCIS
     MREVVQHTRA QIAQLPPSAS RHRAGLTGFI SRLYWHCHFI QKLESEPAIE WHNMHRGYDG
     LREHDFNEAH FEALKAARTG WPMVDACVTM LRETGWLNFR MRAMLVSVAA YPLWLHWRPV
     GEWLATQFLD YEPGIHWSQL QMQSGTTGIN TTRVYNPIKQ AQDHDPHGRF VRQWLPELRQ
     VPDTWLFEPW LMPHTMQVHL GVFVGTDLAQ PVVDLTQATR EAKQLLHSRR QTDEVKAAKK
     AVVDKHASRK NWGTSTSARR TPTRKATRAS ADTTQAAKAQ LGFDF
//