ID A0A2M6VH21_9BURK Unreviewed; 631 AA.
AC A0A2M6VH21;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Propionate--CoA ligase {ECO:0000313|EMBL:PIT77748.1};
GN ORFNames=B9Z42_04670 {ECO:0000313|EMBL:PIT77748.1};
OS Limnohabitans sp. B9-3.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Limnohabitans.
OX NCBI_TaxID=1100707 {ECO:0000313|EMBL:PIT77748.1, ECO:0000313|Proteomes:UP000228506};
RN [1] {ECO:0000313|EMBL:PIT77748.1, ECO:0000313|Proteomes:UP000228506}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B9-3 {ECO:0000313|EMBL:PIT77748.1,
RC ECO:0000313|Proteomes:UP000228506};
RA Kasalicky V., Mehrshad M., Andrei S.-A., Salcher M., Kratochvilova H.,
RA Simek K., Ghai R.;
RT "Unexpected and diverse lifestyles within the genus Limnohabitans.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIT77748.1}.
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DR EMBL; NESI01000002; PIT77748.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M6VH21; -.
DR OrthoDB; 9766486at2; -.
DR Proteomes; UP000228506; Unassembled WGS sequence.
DR GO; GO:0050218; F:propionate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR012694; Propion_PrpE.
DR NCBIfam; TIGR02316; propion_prpE; 1.
DR PANTHER; PTHR43347; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43347:SF3; ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:PIT77748.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000228506}.
FT DOMAIN 5..58
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 60..448
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 513..596
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 631 AA; 69328 MW; 8D3715BDADAE4458 CRC64;
MVAFADFHRR SIEDRDAFWS EQAQLIDWQT KPQQICDYSN PPFAKWFVGG TTNLCHNAVD
RHLADRADQA ALIFVSTETD QEHTYTYRDL HAEVQRMAAI LKAQGVTKGD RVLIYMPMIA
EAAFAMLACV RIGAIHSVVF GGFASHSLAT RIEDATPKVI ISADAGSRGG KVIPYKHLLD
EAIRLSSHKP GKVLMVDRKL APFTPVADRD LDYATERAQH MDTVVPCEWV ESTHPSYTLY
TSGTTGKPKG VQRDTAGYTV ALASSIPHIY QGKPGGTFFC TSDIGWVVGH SYIIYGPLIG
GMATIMYEGL PIRPDGGIWW SLVEKYKVNV MFSAPTAIRV LKKQDPALLS KYDLSSLQAL
FLAGEPLDEP TAKWISEGLN GKPIIDNYWQ TETGWPILTI CNGVEKAESK FGSPGKAVYG
YNVKLVDDQT GEELTGANQK GVLTIEGPLP PGNLQTIWGD DKRFVSTYWS TVPNKLVYNT
FDWAVRDEDG YFFILGRTDD VINVAGHRLG TREIEESISS HPNIAEVAVV GVADQLKGQV
AMAFAIAKDT SGLTDDAARS KLEAEIMKVV DTQLGALARP ARVMFVTALP KTRSGKLLRR
AIQAVCEKRD PGDLTTIDDP TALTQIQDQI A
//
