ID A0A2M6VMG5_9BURK Unreviewed; 492 AA.
AC A0A2M6VMG5;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Succinate-semialdehyde dehydrogenase (NADP(+)) {ECO:0000313|EMBL:PIT79608.1};
GN Name=gabD {ECO:0000313|EMBL:PIT79608.1};
GN ORFNames=B9Z41_06370 {ECO:0000313|EMBL:PIT79608.1};
OS Limnohabitans sp. JirII-31.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Limnohabitans.
OX NCBI_TaxID=1977908 {ECO:0000313|EMBL:PIT79608.1, ECO:0000313|Proteomes:UP000228925};
RN [1] {ECO:0000313|EMBL:PIT79608.1, ECO:0000313|Proteomes:UP000228925}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JirII-31 {ECO:0000313|EMBL:PIT79608.1,
RC ECO:0000313|Proteomes:UP000228925};
RA Kasalicky V., Mehrshad M., Andrei S.-A., Salcher M., Kratochvilova H.,
RA Simek K., Ghai R.;
RT "Unexpected and diverse lifestyles within the genus Limnohabitans.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PIT79608.1}.
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DR EMBL; NESA01000003; PIT79608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M6VMG5; -.
DR OrthoDB; 6187633at2; -.
DR Proteomes; UP000228925; Unassembled WGS sequence.
DR GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:InterPro.
DR GO; GO:0009450; P:gamma-aminobutyric acid catabolic process; IEA:InterPro.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010102; Succ_semiAld_DH.
DR NCBIfam; TIGR01780; SSADH; 1.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000228925}.
FT DOMAIN 27..484
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 264
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 492 AA; 53121 MW; C88DAD1B8EC21F69 CRC64;
MPMKITPLSR LNDPTLLKTD ALINGQWVQG SSRFDVHDPA TGEKLVDVAN LGTAEAQAAI
AAANAAWPAW RSKTGKERSI ILRKWFDLLM ANVDDLGRLM TAEQGKPFAE AKGEVTYGAS
FVEWYAEEAK RVNGETLPQF DNNRRLMVLR QPIGVCAAIT PWNFPLAMIT RKVAPALAAG
CPVVIKPAEL TPLTALAAAE LALRAGIPAG VLNVLTADSS NSVAIGKVLC DSDVVRHLSF
TGSTEVGRIL MAQSAPSVKK LALELGGNAP FIVFDDADID SAVEGAMASK YRNAGQTCVC
ANRIYVQDAV YDEFVQKFAH KVKALKVGNG FDEGVMQGPL IEPAAIEKVE RHVRDALSKG
GKLLTGGHKM DGQFFQPTVI AEARADMLCA KEETFGPFAP VFRFKHEQEA IDAANHTEFG
LASYFYSRDV GRIFRVSEAL EYGMVGINVG IIATEHVPFG GVKQSGLGRE GSHHGMDEYL
ELKYLCIGDI AK
//
