ID A0A2M8GXJ0_9VIBR Unreviewed; 345 AA.
AC A0A2M8GXJ0;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=CSW98_10760 {ECO:0000313|EMBL:PJC86054.1};
OS Vibrio sp. HA2012.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=1971595 {ECO:0000313|EMBL:PJC86054.1, ECO:0000313|Proteomes:UP000232179};
RN [1] {ECO:0000313|EMBL:PJC86054.1, ECO:0000313|Proteomes:UP000232179}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HA2012 {ECO:0000313|EMBL:PJC86054.1,
RC ECO:0000313|Proteomes:UP000232179};
RA Wang K.;
RT "The draft genome sequence of Vibrio sediminis HA2012.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJC86054.1}.
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DR EMBL; PFXK01000005; PJC86054.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M8GXJ0; -.
DR OrthoDB; 9770982at2; -.
DR Proteomes; UP000232179; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR032780; DNA_pol3_delt_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF14840; DNA_pol3_delt_C; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000232179}.
FT DOMAIN 20..189
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 213..332
FT /note="DNA polymerase III subunit delta C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14840"
SQ SEQUENCE 345 AA; 39521 MW; FC66ACF2D06F5B1B CRC64;
MRIFADKLPA QLQRQLQNVY LIFGNEPLLL SESRDAIYTA AKAAGYLEKF YFSADAQLEW
DQVFDCCQAL SLFSSRKIIE LEIPESGVNA ATGKALLELS AYLNPDVILI LFGNKLTRQQ
ESTKWFKTLH QQGAWVSCLS PDIQRLPQFV RFRCQKLGLY PDDEALQMLA QWHEGNLLAL
VQSLEKLALL YPDGKLTLVR LEEALNRHNH FTPFHWVDAL LAGQLNRAQR ILRQLQAEGT
EAIILLRTLQ KELLLLISYK RELQSMLPGQ LFDKHRVWQN KRPLYNAALQ RLTPGHLNRI
LKLLTQAEII AKTQYEQSPW PLISQISLEL CSPEAAKVIP LPIES
//
