ID   A0A2M8LPF6_9ACTN        Unreviewed;      1559 AA.
AC   A0A2M8LPF6;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=Type IV secretion protein Rhs {ECO:0000313|EMBL:PJE93838.1};
GN   ORFNames=CUT44_32065 {ECO:0000313|EMBL:PJE93838.1};
OS   Streptomyces carminius.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2665496 {ECO:0000313|EMBL:PJE93838.1, ECO:0000313|Proteomes:UP000230407};
RN   [1] {ECO:0000313|EMBL:PJE93838.1, ECO:0000313|Proteomes:UP000230407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TRM SA0054 {ECO:0000313|EMBL:PJE93838.1,
RC   ECO:0000313|Proteomes:UP000230407};
RA   Wang Y., Luo X., Wan C., Zhang L.;
RT   "Streptomyces carmine sp. nov., a novel actinomycete isolated from Sophora
RT   alopecuroides in Xinjiang, China.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJE93838.1}.
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DR   EMBL; PGGW01000071; PJE93838.1; -; Genomic_DNA.
DR   Proteomes; UP000230407; Unassembled WGS sequence.
DR   Gene3D; 2.180.10.10; RHS repeat-associated core; 2.
DR   InterPro; IPR045351; DUF6531.
DR   InterPro; IPR022385; Rhs_assc_core.
DR   InterPro; IPR031325; RHS_repeat.
DR   InterPro; IPR049082; T7SS_signal.
DR   InterPro; IPR028048; Tox-HNH-EHHH.
DR   InterPro; IPR006530; YD.
DR   NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR   NCBIfam; TIGR01643; YD_repeat_2x; 13.
DR   PANTHER; PTHR32305; -; 1.
DR   PANTHER; PTHR32305:SF15; PROTEIN RHSA-RELATED; 1.
DR   Pfam; PF20148; DUF6531; 1.
DR   Pfam; PF05593; RHS_repeat; 14.
DR   Pfam; PF21725; T7SS_signal; 1.
DR   Pfam; PF15657; Tox-HNH-EHHH; 1.
DR   SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230407}.
FT   DOMAIN          12..261
FT                   /note="Putative T7SS secretion signal"
FT                   /evidence="ECO:0000259|Pfam:PF21725"
FT   DOMAIN          414..485
FT                   /note="DUF6531"
FT                   /evidence="ECO:0000259|Pfam:PF20148"
FT   DOMAIN          1487..1554
FT                   /note="HNH/Endo VII superfamily nuclease toxins"
FT                   /evidence="ECO:0000259|Pfam:PF15657"
FT   REGION          202..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          386..417
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          225..252
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        386..403
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1559 AA;  170610 MW;  2B6EDE197D134DAC CRC64;
     MGWRDFVPDV IEDKVEEGVE LVGEGIEELG DVGADLLEDA GWESGADWVR DKSRSAANAL
     GADVDELQLG QTEDPKKLIY GSASKLRSTA DHLKDFRQAF DNVGKGIKGL DSSGLEGEAA
     EAFRTKAAEE PPRWFKAADA CEKAAGALED FASTVEWAQG RAKEAIAKYK AALKASEDAR
     KEHNGKVDAY NKAADAYNAK VKAGEDPGAK PTPPGEFKDP GPAKAEAAEE ILAEARKQRN
     EAAEKARTAV QAARDAAPAK PSYAEQAKYG VIGVGTDLTH FYGGVIKGTT GLVSFARSIN
     PTDPYNITHP AEYLTTLNST VAGLVQVAND PWGTGRQMVS DFMKDPAEGL GRLAPDVALT
     VATGGAGAGV RGVRIAAEAA DLASDANRGR RALDNDGPEQ HGTEPGDRNS GGTDPVDLAT
     GRMFLPQTDV SLPGALPLVF RRHVESGYTA GRWFGPSWAS TVDQRLEIDA EGVVFVAEDG
     RLLAYPHPAP GVPTLPSAGS ARMPLERTPD GGYTLTDPET GHVRHFAPPA GAEPGGDGTA
     LLEQLTDRAG HQIVFVHDEA TGAPARIEHS GGYTLHLTVE DGRVTALSLA GQVIKRYGYT
     DGHLTEVADS AGRPLRFEYD DEARVIAWVD SNGRRYDYVY DNLHRCIGEG GTEGHMQVRI
     TYDGTDPATG HKVTTLTTPQ GHATRHVIDD RCRTVATTDP LGHTTRFAYD ERDRLVSQTD
     PLGRTVAYAH DEHGRIVSVT RPDGREITVT RNELGLPTEV READGSVWRH TYDERGNRTA
     TTDPAGATTR YTYDTHGHLT SVTNALGDTT RVRCDAAGLP VEITDPLGAV LRYERDNFGR
     PIALTDPLGA VTRLTWTTEG KLARRVDPDG VQEGWEYDGE GNCVRHTDAA GGVTTYEYTH
     FDLLTARTGP DGARYTFAHD AELRLAQVTN PQGLTWSYVY DPAGRLTAET DFDDRTVTYT
     HDPAGQLTAR TTPLGETIAY QRDELGRLVR KEAGERVTTF AYDALGRPVE AIGPDTEVRW
     QRDKLGRTKT EMADGRVLTF SYDALGRRTR RTTPTGATTT YAYDAAGNRT TLTTGGHTLD
     FTHDAIGRET ARRIGEDLTL TQLWDPAGRL TDQTLTGPDP SAPVQQRSYH YRADGYLTAV
     DDLLTGHRVL DLDATGRVTA VHAQGWSETY AYDAAGNQTS AAWPTTHAAA DATGERTYTG
     TRLTRAGRIR YEHDPAGRLT LRRRTRLSKK PDTWHYTWDT EDRLTSVVTP DGTVWRYLYD
     PLGRRIAKQR LAPGGETVAE QVDFTWDGPV LIEQTTTAPD LPHPVTLTWE HDGFTPLTQT
     ERLTDDATQA EIDQRFFAII TDLVGTPTEL VDESGHLAWH TRTTLWGTTT WNRDATTYTP
     LRFPGQYHDP ETGLHYNYFR YYDPTTARYA TPDPLGLAPA PNPATYPHNP HTWTDPLGLA
     PEYVQRTRGD AQAQALRDAG IPEGAEPIDV DDWVPATGPE WQGSKQLLDD NHQPIYYREE
     YYETPSGDLI VYQDHWFGHQ KPGEPGYQPP HVHVRPFDDP RNGQIPGCEE HYYYDPKLG
//