ID A0A2M8LS04_9ACTN Unreviewed; 558 AA.
AC A0A2M8LS04;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Succinic semialdehyde dehydrogenase {ECO:0000313|EMBL:PJE94746.1};
GN Name=gabD2 {ECO:0000313|EMBL:PJE94746.1};
GN ORFNames=CUT44_26665 {ECO:0000313|EMBL:PJE94746.1};
OS Streptomyces carminius.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2665496 {ECO:0000313|EMBL:PJE94746.1, ECO:0000313|Proteomes:UP000230407};
RN [1] {ECO:0000313|EMBL:PJE94746.1, ECO:0000313|Proteomes:UP000230407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRM SA0054 {ECO:0000313|EMBL:PJE94746.1,
RC ECO:0000313|Proteomes:UP000230407};
RA Wang Y., Luo X., Wan C., Zhang L.;
RT "Streptomyces carmine sp. nov., a novel actinomycete isolated from Sophora
RT alopecuroides in Xinjiang, China.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJE94746.1}.
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DR EMBL; PGGW01000068; PJE94746.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M8LS04; -.
DR Proteomes; UP000230407; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000230407}.
FT DOMAIN 66..522
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 295
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 558 AA; 58611 MW; 01BA6481DA69769A CRC64;
MTESPGTTAR AAGVAGTAGA AAGPVRPAPA PDGNPVAPAP TAARTAADVV TADLVARLTE
DVTGSGTTAC HTPFTGEKLA DLPEAAPEDV AAAFARARRA QRRWAARPAR ERAAVLLRFH
DLLLSRQREV LDLNQLETGK ARLHAHEEVQ AVAVAARYYG RTAPAHLRPR RRAGAFPVLT
KTLELRHPKG VVGLIAPWNY PLELSVGDAL PAFAAGNAVV MKPDTETALT ALWARRLLIE
AGLPADVWQV VVGDGPVVGP AVVEHADYVS FTGSTRTGRE VARRAADRLV GCSLELGGKN
AMIVLADADP DRAAAGAVRG AFSSAGQLCI SIERLYVHAS VADAFTERLV ARTRALRLGT
ALAYGADMGS LASERQLRTV TEHVAEAVAK GAKVLAGGRP RPDVGPFFHE PTVLAGVTAD
MAVCGEETFG PVVSVHRFTD EDEAVALANA TPYGLNASVW SRNGRRARAL ATRLRAGTVN
VNEAYGAAYG SVQAPMGGMG DSGLGRRHGA EGILKYTEAQ TVAQQRVVPL APSFGMDDER
YAAFMNTSLR ALKALRLR
//
