ID A0A2M8M2C9_9ACTN Unreviewed; 347 AA.
AC A0A2M8M2C9;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=DNA polymerase III subunit epsilon {ECO:0000313|EMBL:PJE98362.1};
GN ORFNames=CUT44_06485 {ECO:0000313|EMBL:PJE98362.1};
OS Streptomyces carminius.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2665496 {ECO:0000313|EMBL:PJE98362.1, ECO:0000313|Proteomes:UP000230407};
RN [1] {ECO:0000313|EMBL:PJE98362.1, ECO:0000313|Proteomes:UP000230407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRM SA0054 {ECO:0000313|EMBL:PJE98362.1,
RC ECO:0000313|Proteomes:UP000230407};
RA Wang Y., Luo X., Wan C., Zhang L.;
RT "Streptomyces carmine sp. nov., a novel actinomycete isolated from Sophora
RT alopecuroides in Xinjiang, China.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJE98362.1}.
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DR EMBL; PGGW01000019; PJE98362.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M8M2C9; -.
DR Proteomes; UP000230407; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProt.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd06127; DEDDh; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR006054; DnaQ.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; TIGR00573; dnaq; 1.
DR PANTHER; PTHR30231; DNA POLYMERASE III SUBUNIT EPSILON; 1.
DR PANTHER; PTHR30231:SF4; PROTEIN NEN2; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50172; BRCT; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000230407}.
FT DOMAIN 256..334
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 219..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 347 AA; 38071 MW; 5B5F25E1F97E3EB0 CRC64;
MLEDQSAPRL RPTARPTARH AARPSTPAWP VEYPESYAVV DVETTGLARD DRIVSAAVYR
LDARGDVIDH WYTPVNPQRD PGPVWIHGLT SEMLADAPVF AEVAEEFAER LRDRVLVAHN
AVFDWSMIAR EYARARLTPP VRQRLCTIAL SKELGLPLAN HRLETLAAHY GVVQHRAHHA
LDDARVLAEA FRPSLRLAAA DGIRLPLLAC QPLTEWTDSV TAPDAHGGRP RSYAGSWRPS
RRRPACPYPN PGRYEPGGPL VQGMRVAISG DTSTDRELLE DRAVEAGLHI ATSVSRLTSL
LVTNDPDSGT SKIVKARAHG TPVIDEAAFT QLLRDVAPAA EPPAPRE
//
