ID A0A2M8M2F1_9ACTN Unreviewed; 688 AA.
AC A0A2M8M2F1;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE RecName: Full=Mg-protoporphyrin IX chelatase {ECO:0000256|ARBA:ARBA00030759};
GN ORFNames=CUT44_06585 {ECO:0000313|EMBL:PJE98377.1};
OS Streptomyces carminius.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2665496 {ECO:0000313|EMBL:PJE98377.1, ECO:0000313|Proteomes:UP000230407};
RN [1] {ECO:0000313|EMBL:PJE98377.1, ECO:0000313|Proteomes:UP000230407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRM SA0054 {ECO:0000313|EMBL:PJE98377.1,
RC ECO:0000313|Proteomes:UP000230407};
RA Wang Y., Luo X., Wan C., Zhang L.;
RT "Streptomyces carmine sp. nov., a novel actinomycete isolated from Sophora
RT alopecuroides in Xinjiang, China.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the Mg-chelatase subunits D/I family.
CC {ECO:0000256|ARBA:ARBA00005799}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJE98377.1}.
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DR EMBL; PGGW01000019; PJE98377.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M8M2F1; -.
DR Proteomes; UP000230407; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd01451; vWA_Magnesium_chelatase; 1.
DR Gene3D; 1.10.8.80; Magnesium chelatase subunit I, C-Terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041702; BchD/ChlD_VWA.
DR InterPro; IPR041628; ChlI/MoxR_AAA_lid.
DR InterPro; IPR012804; Cob_chelat_sub_put.
DR InterPro; IPR000523; Mg_chelatse_chII-like_cat_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR NCBIfam; TIGR02442; Cob-chelat-sub; 1.
DR PANTHER; PTHR35023; CHELATASE-RELATED; 1.
DR PANTHER; PTHR35023:SF1; MG-PROTOPORPHYRIN IX CHELATASE; 1.
DR Pfam; PF17863; AAA_lid_2; 1.
DR Pfam; PF01078; Mg_chelatase; 1.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000230407}.
FT DOMAIN 500..636
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 333..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 688 AA; 71856 MW; FAD761319CABC3B2 CRC64;
MNVPYPFSAV VGMADLRLAL LLNAVSPAVG GVLVRGEKGT AKSTMVRALA ALLPRIEVVP
ECRFSCDPHR PDPRCPDGPH ETGRGTARAA RLVELPVGTS EDRLVGALDI ERALSEGVKA
FEPGLLARAH RGVLYVDEVN LLQDFLVDSL LDAAAMGASH VEREGVSVRH AARFLLVGTM
NPEEGELRPQ LLDRFGLTVE VTASRETGER MEVVRRRLAY EAGPAGFTAR WAGEEAALRE
RIAAARALLP EVRLGDAALR QIAATCAAFE VDGMRADIVM ARTATALAAW AGRTEVAAED
VRQAALLALP HRRRRNPFDA PGLDEEKLDE TLRQHGGGNE EPDPDGPDGG PGGPGDGGGD
GGGGQPPQDG PPAPPDPSAP PEHSEPSVPG QSRGDEETGG RGGGAGEQAP ARAGEPFRAR
SLSVPGVGEG AAGRRSRART SQGRTTGARR PRGTLGRLHL AATVRAAAPH QRARGRSGPG
LVLRRDDLRE AHTEGKESNL VLFVVDASGS MAARQRMSAV KGAVLSLLLD AYQRRDKVGL
VTFRGADAAV ALPPTSSVDA AAARLESLPT GGRTPLAAGL LKAREVLRIE RLRDPARRAL
LVAVTDGRAT GGPEPVARAR QAARLLAVDG TASVVVDCES GPVRLGLAGA LAAELDGPAV
TLEELRADAV AGLVRSAQNP NRSRGRAA
//
