ID A0A2M8M2Z8_9ACTN Unreviewed; 954 AA.
AC A0A2M8M2Z8;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=ABC transporter ATP-binding protein {ECO:0000313|EMBL:PJE98579.1};
GN ORFNames=CUT44_06390 {ECO:0000313|EMBL:PJE98579.1};
OS Streptomyces carminius.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=2665496 {ECO:0000313|EMBL:PJE98579.1, ECO:0000313|Proteomes:UP000230407};
RN [1] {ECO:0000313|EMBL:PJE98579.1, ECO:0000313|Proteomes:UP000230407}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRM SA0054 {ECO:0000313|EMBL:PJE98579.1,
RC ECO:0000313|Proteomes:UP000230407};
RA Wang Y., Luo X., Wan C., Zhang L.;
RT "Streptomyces carmine sp. nov., a novel actinomycete isolated from Sophora
RT alopecuroides in Xinjiang, China.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJE98579.1}.
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DR EMBL; PGGW01000019; PJE98579.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M8M2Z8; -.
DR Proteomes; UP000230407; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03213; ABCG_EPDR; 1.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.60.200.20; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR48041:SF91; ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A; 1.
DR PANTHER; PTHR48041; ABC TRANSPORTER G FAMILY MEMBER 28; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF00498; FHA; 2.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00240; FHA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:PJE98579.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000230407};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 698..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 737..758
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 778..801
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 821..841
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 848..869
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 921..944
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 138..187
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 301..351
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 383..624
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 228..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..264
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 954 AA; 102624 MW; C30A105BCA7E3CFC CRC64;
MIPTVSSTGA VPYAPSVPRT PGRRPTRRRP GDPPRPPRCA LSIRGVHRPG YPLVRGFLRC
LPPPAPGRGA DRSGSATIHR GGCLRGRVAW NSASTIIRHP RLLVGGGSSG DNFVGHGVSE
LVVQLNGRTW TLDPSRSYTL GRDPQGDLVV DDARVSWRHA TLSWSGTAWT VEDQGSTNGT
YARGGRVRRL EVGAGSVVHL GNAADGPLLE FSAAAAGVPA AGAPAAVAAP QAPARQPQQY
GGGPGPGPGQ PPAAPAPQQQ VPPQHTPRPD QEGMSPQSGA PLHGDHRSPT TFHQFALGRV
MRIGRALENE LVVSDLQVSR HHAEFRSTPD GRFEIRDLGS HNGTYVNGQP LPKSGSAVIG
PDDVVGVGHS AFRVVGDRLE EFVDTGEVSF SARHLTVKVD GGKVILNNVS FGVPEKSLVA
VIGPSGSGKS TLLRALTGYR PADIGEVLYD NRNLYKQFAE LRQRIGLVPQ DDILHKELTV
RTALRYAAKL RFPGDVAGAE RNARVEEVLA ELKLDIHAAK KITSLSGGQR KRVSVALELL
TKPSLIFLDE PTSGLDPGMD RDVMQLLRGL ADDGRTVLVV THSVAELALC DRLLVMAPGG
GVAYFGPPDE ALNFFGYESW ADVFSAFENY RDYDWIGRWQ GSQHYRRYAA DIDAPAPQAY
QYAQYAGPAA RPPKPQSWGS QLWTLTRRYT SVIASDKGFL ALMVILPVIL GTVSTVIPTE
YGITRNPNGF NQHAGTILLI LAVGMCLAGA ANSVRELVKE RVIYERERAT GLSRSAYLMS
KVIVLGVITA FQGVIISVIG FSTRELPDEG LILPANVELC VGIIAFGLTS MMIGLVISSL
VKTSEMTMPL LVGFAIVQLV FTGVLFQVFD SPGIEQLAWL MPSRWAVGVL GATVDLSRTM
APWDRENPTN LDPLWEHSTG VWVMDLLILL AMGVACGFAV ARLLRRHEPE VMRG
//
