ID   A0A2M8MXB3_9RHOB        Unreviewed;       972 AA.
AC   A0A2M8MXB3;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Sarcosine oxidase subunit alpha {ECO:0000313|EMBL:PJF08846.1};
GN   ORFNames=CUR21_10170 {ECO:0000313|EMBL:PJF08846.1};
OS   Pseudorhodobacter sp. MZDSW-24AT.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Paracoccaceae; Pseudorhodobacter.
OX   NCBI_TaxID=2052957 {ECO:0000313|EMBL:PJF08846.1, ECO:0000313|Proteomes:UP000230388};
RN   [1] {ECO:0000313|EMBL:PJF08846.1, ECO:0000313|Proteomes:UP000230388}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MZDSW-24AT {ECO:0000313|EMBL:PJF08846.1,
RC   ECO:0000313|Proteomes:UP000230388};
RA   Mayilraj S.;
RT   "Pseudorhodobacter sp. nov., strain MZDSW-24AT genome sequence and
RT   assembly.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJF08846.1}.
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DR   EMBL; PGOI01000008; PJF08846.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M8MXB3; -.
DR   OrthoDB; 5287468at2; -.
DR   Proteomes; UP000230388; Unassembled WGS sequence.
DR   GO; GO:0008115; F:sarcosine oxidase activity; IEA:InterPro.
DR   GO; GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
DR   Gene3D; 3.10.20.440; 2Fe-2S iron-sulphur cluster binding domain, sarcosine oxidase, alpha subunit, N-terminal domain; 1.
DR   Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR042204; 2Fe-2S-bd_N.
DR   InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006277; Sarcosine_oxidase_asu.
DR   InterPro; IPR041117; SoxA_A3.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   NCBIfam; TIGR01372; soxA; 1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR   Pfam; PF12831; FAD_oxidored; 1.
DR   Pfam; PF13510; Fer2_4; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF17806; SO_alpha_A3; 1.
DR   PRINTS; PR00368; FADPNR.
DR   PRINTS; PR00469; PNDRDTASEII.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230388}.
FT   DOMAIN          493..578
FT                   /note="SoxA A3"
FT                   /evidence="ECO:0000259|Pfam:PF17806"
FT   DOMAIN          597..852
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          879..964
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   972 AA;  104101 MW;  3E85857CA2DEFD6F CRC64;
     MRIDGKGRID RTRPVTFTFD GRPYAGYRGD TLASALIAND VRVVGRSFKY HRPRGILTAG
     SEEPNALVEV VGPANQTPNT RATVQELFEG LVARSQNRWP SLSLDLLEVN DLAAPFLSAG
     FYYKTFMWPR RFWEGIYEPL IRRAAGLGRL SGKHDEGVYE KAWAHCDLLV IGAGPAGLMA
     ALVAARAGAD VILCDESAEM GGRLLSDEGQ IDGMPAADWT AAVLAELASL PNLRLMPRTT
     VTGAYDDGTY GALERVGLHR SPRPNLPREC FWRIVAKRSI LAAGALERGI AFQDNDRPGV
     MLAGSLATYL NRYGVSPGKR VALFANNGSV RATARSLKAA GVEVVAILDS RPDAPDEPGI
     PVHKGATVLR ARGRMGLHSL SFAHEGRVHA LEVDCLGVSG GWNPAVHLTC HRNGRPRWSD
     ELAAFVPMEG AVPGMRVAGA AAGSFSTHAC LASGAEAARE SLAALGRDGG ALDLPRAEDA
     PYRIAPLWTV PGKGRAWLDF ANDVTVKDVT LAAQEGFRSV EHMKRYTTQG MAPDQGKSSN
     VAALAVLADA TGRGIPETGT TTFRPPYTPV SIAAMGAGGR GAGFAPQRFL TSDQASRDRA
     APMVEAGLWY RPSYFPKPQE TTWREACDRE VRMVRETVGV SDVSTLGKID VQGPDAARFL
     DFVYSNTMST LPVGKVRYGL MLREDGHVLD DGTCARLGAQ HWLITTTTAA AGLVMRHLDF
     VHQAFCAGWQ LRFVSVTEAW AQFAIAGPQA RALVASALGR APELGFMGCA PVTVQGVAGR
     LFRISFSGEE GYELAVPTRF GEALFRDLVA RAETMGGGPY GMEALNVLRI EKGFITHAEI
     HGRVTAFDIG MEKMVSGKKD CIGKAAAMRP GMQGAARAQM VGLKPLSDDV ITAGAHLFAQ
     GVDLGRETSA GYVTSVGYSP TLHSHLALGF LANGRARHGE TVRLVDRLRG VDVLCTVTSP
     VFHDPKGEKL RA
//