ID A0A2M8RYT6_9PAST Unreviewed; 644 AA.
AC A0A2M8RYT6;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Macrolide ABC transporter permease/ATP-binding protein MacB {ECO:0000313|EMBL:PJG84063.1};
GN ORFNames=CVP04_01015 {ECO:0000313|EMBL:PJG84063.1};
OS Caviibacterium pharyngocola.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Caviibacterium.
OX NCBI_TaxID=28159 {ECO:0000313|EMBL:PJG84063.1, ECO:0000313|Proteomes:UP000230282};
RN [1] {ECO:0000313|EMBL:PJG84063.1, ECO:0000313|Proteomes:UP000230282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7_3 {ECO:0000313|EMBL:PJG84063.1,
RC ECO:0000313|Proteomes:UP000230282};
RA Christensen H.;
RT "Reclassification of Bisgaard taxon 5 as Caviibacterium pharyngocola gen.
RT nov., sp. nov.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. Macrolide
CC exporter (TC 3.A.1.122) family. {ECO:0000256|ARBA:ARBA00038388}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJG84063.1}.
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DR EMBL; PHGZ01000003; PJG84063.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M8RYT6; -.
DR OrthoDB; 9770036at2; -.
DR Proteomes; UP000230282; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03255; ABC_MJ0796_LolCDE_FtsE; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003838; ABC3_permease_dom.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR017911; MacB-like_ATP-bd.
DR InterPro; IPR025857; MacB_PCD.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR30572:SF14; MACROLIDE EXPORT ATP-BINDING_PERMEASE PROTEIN MACB; 1.
DR PANTHER; PTHR30572; MEMBRANE COMPONENT OF TRANSPORTER-RELATED; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF02687; FtsX; 1.
DR Pfam; PF12704; MacB_PCD; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:PJG84063.1};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000230282};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..242
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 644 AA; 70601 MW; B4E264643B244E3D CRC64;
MNIIEIKNIN KYFGEGENRT QVLKDINLEI KKGDFIAIIG QSGSGKSTLM NIIGCLDTAT
SGSYKIEETE VSRLNADQLS DLRRKKFGFI FQRYNLLSTL SAVENVALPA IYAGVDQKTR
LERAALLLEK LGLADRLQNK PNQLSGGQQQ RVSIARALMN GGDIILADEP TGALDSRSGE
TVMEILQQLH REGHTIILVT HDKQVAEFAN RIIEIKDGKI IEDTRKSDLI AQKEETAAPQ
KSRFGFYKDQ FAESFKMSVK AIIAHKLRSL LTMLGIIIGI TSVVCVVALG NGSQQKILAN
INSMGTNTMD IYNGTGFGDR RADKMQNLTV GDSNILAKQS YIESATPNSS VSGTLVYQNE
SFTAQVKGVG DQYFNVKGLS LKQGQFFNDN DVKHNEQVAV IDENTLKQVF NNQNPIGQVL
MLNKKPLRVI GVAATSNNMG MNSSSLNIYI PYSTAMNKIS GNQKIDSITV KVRNEVNSTV
AEKDLTNLLL VRHGKKDFFV MNTDTIKQTI ESTTNTMRLL ISCIALISLV VGGIGVMNIM
LVSVTERTKE IGVRMAIGAR QFNILQQFLI EAVLICLIGG LTGITLSILF GMLFNFFMTD
FTMVFSSASI ISAVLCSTLI GIVFGYMPAK NAAKLNPITA LARE
//
