ID A0A2M8TBY5_9CLOT Unreviewed; 860 AA.
AC A0A2M8TBY5;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Helix-turn-helix transcriptional regulator {ECO:0000313|EMBL:PJI08469.1};
GN ORFNames=CUB90_11610 {ECO:0000313|EMBL:PJI08469.1};
OS Clostridium sp. CT7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=2052574 {ECO:0000313|EMBL:PJI08469.1, ECO:0000313|Proteomes:UP000230839};
RN [1] {ECO:0000313|EMBL:PJI08469.1, ECO:0000313|Proteomes:UP000230839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT7 {ECO:0000313|EMBL:PJI08469.1,
RC ECO:0000313|Proteomes:UP000230839};
RA Xin F., Chen T.;
RT "The draft genome sequence of Clostridium sp. CT7, a unique bacterium
RT capable of producing butanol from glycerol uncoupled acetone and 1,3-
RT propanediol formation.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJI08469.1}.
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DR EMBL; PETE01000002; PJI08469.1; -; Genomic_DNA.
DR RefSeq; WP_066021356.1; NZ_PETE01000002.1.
DR AlphaFoldDB; A0A2M8TBY5; -.
DR OrthoDB; 9789465at2; -.
DR Proteomes; UP000230839; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR44688; -; 1.
DR PANTHER; PTHR44688:SF16; TRANSCRIPTIONAL ACTIVATOR PROTEIN BJAR1; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000230839}.
FT DOMAIN 793..858
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
SQ SEQUENCE 860 AA; 100953 MW; 70E2975A14321A44 CRC64;
MKNEFNLIRT KLIAPIPRKN YIKREGIINE LKNIFDYKIT IVKGAAGSGK STLLSSFIKD
KKLKHVKWIN LDSENNEIYS FWYYFIEAIS DYLPGKSEKL INNLNGMANS EEILEIISYM
INKLCIEEDI LIVFDDYHHI KDKNLNLTVK YLIKYSPQNV HYAFLTREEF PIYLGELRVR
DELLEINETE LRFSKAECSD FMHNTLKLDI SEEDMNKIFN ISEGWIGGLQ FTALALKNKG
HIEKINVLNK YVIEYLTEEI LKGLNSRESK FLIKTSILKY FNSDLTDYVL EITDSTDIIN
SLVDKNLFII TLNEEENVFR YHHLFNEFLN ISFNKLAEEE KKVLHLRAYN FLKENGDVNE
SIRHLFSIKA YEKAIPLIEK NISDPKSWIH MKELPLENLI TSNELIVQRI FYHFSNLQVD
ECKDIINYIE KNGSREAKSL ANMSKIYVYN YCSGVKEEDL KLVEKLKLSE ITKAVIYLNM
QPIFLSKNEY EKVIKYAVEA DKIAKKHNMF FLSVFAKCQI AIILEDMGEY SKVMDKYKDI
KILTDKSGFN GAYKSLYYLG VAGIYMKRYE IAKSEKCLKL AAEKIGQKHA FTKPGIIYNE
MELRFIKHEF EEGKKIVDGL SKIYVDSFIP LQICTAEFRY MLPMKFYQKE DLHQFKSMFE
KEKNYGKYIR PEDKIVYSRV LYLLSEKHEA IKTLDEVLEF CRKYSIITNL IDGIIVKIML
LKEDFELKKR EIYNLLRESL HYSIKNEYLR VYVIEGKPLL NLIKKLKNDK NIELTSKEKE
FIQKIIDIEE PNETKKDELL SEREKEVLSV LCEGHSNKEI GEILNISLAT VKTHILNIYS
KLQVSNRVQA VEKAKKVGLK
//
