ID   A0A2M9BJ62_9ACTN        Unreviewed;       833 AA.
AC   A0A2M9BJ62;
DT   25-APR-2018, integrated into UniProtKB/TrEMBL.
DT   25-APR-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Glycine cleavage system aminomethyltransferase T {ECO:0000313|EMBL:PJJ57990.1};
GN   ORFNames=CLV56_2233 {ECO:0000313|EMBL:PJJ57990.1};
OS   Mumia flava.
OC   Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC   Nocardioidaceae; Mumia.
OX   NCBI_TaxID=1348852 {ECO:0000313|EMBL:PJJ57990.1, ECO:0000313|Proteomes:UP000230842};
RN   [1] {ECO:0000313|EMBL:PJJ57990.1, ECO:0000313|Proteomes:UP000230842}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 27763 {ECO:0000313|EMBL:PJJ57990.1,
RC   ECO:0000313|Proteomes:UP000230842};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT   (KMG-II): From Individual Species to Whole Genera.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the GcvT family.
CC       {ECO:0000256|ARBA:ARBA00008609}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PJJ57990.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PGEZ01000001; PJJ57990.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2M9BJ62; -.
DR   Proteomes; UP000230842; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR028896; GCST/YgfZ/DmdA.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR   PANTHER; PTHR43757:SF9; SARCOSINE DEHYDROGENASE; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF103025; Folate-binding domain; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000313|EMBL:PJJ57990.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000230842};
KW   Transferase {ECO:0000313|EMBL:PJJ57990.1}.
FT   DOMAIN          13..392
FT                   /note="FAD dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF01266"
FT   DOMAIN          397..449
FT                   /note="FAD dependent oxidoreductase central"
FT                   /evidence="ECO:0000259|Pfam:PF16350"
FT   DOMAIN          452..725
FT                   /note="Aminomethyltransferase folate-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01571"
FT   DOMAIN          746..825
FT                   /note="Glycine cleavage T-protein C-terminal barrel"
FT                   /evidence="ECO:0000259|Pfam:PF08669"
SQ   SEQUENCE   833 AA;  89636 MW;  3F823C2CF8AE5A61 CRC64;
     MSASRSTPLA QPRVVIIGLG VVGAALADEL VLRGLRSVTV LEQGPLYATG GSSSHAPGFV
     FQTNPNRTTS ALAARTLGKL DRLDLGGAWI SKRVGGLELA RTPERLRELA RRHGLASAGG
     IESALVGPEE CARLWPGLDP SVVLGGFHTP TDAVVKSARA VEWQARRAEA GGAVVRGHSR
     VVGIRTAAGR VTGVEVVGVP SAPDATPEVV PADVVVCCAG LWGPQMAREL LGFEIPMMPM
     EHGFAWSTPI ASRAALDEDV EVERVMLRHQ DHAMYLREWG STVAIGAYEH RPIPVEPERI
     ASADEFAATG VHPAMHPFTL ADFEPTWREA QTLIPELRGV GLDGSRAFNG IFSFTPDGGP
     MLGPVTGTDG LWLAQAVWVS QSAGVAQVVA DWLVHDDPGI DTHTLDHRRF DPAVVSHDFT
     VERAEEAYDE VYDIVHPRAS TLRLRGLRTT PFYERQRELG AVFAEANGWE RPLWFEANAG
     FEGPPVAERD AWSAQHWSPI AAAEAYAARN AVALFDMSAL ARLEVSGPGA EAYLSGLLTR
     PPGRSVGTIV YGLLLDGAGG VLSDVTVARL GPEEFHLGVN GPLDRAWLTA HLPDDGSVRI
     RDVASGACGL GLWGPAARDV LATLTPDDVS HAGFGFYRAR RIRVAGVPVL ALRLSYVGEL
     GWELYAPAEF GRRLWDALWE SGRPHGIVAA GRRAFESLRL EKGYRLWGTD VTREHAPDEA
     GLSFAVRDDG REFVGRDALA TRPATRRLTC LTLDDPRRVV LGGEPVRSGD EVVGYVTSAD
     HGYTTHTSIA YAWVPAELAV VGTALTVEWF GEQLGATVTA EPIFDPDMKH MRR
//