ID A0A2M9CZ59_9CELL Unreviewed; 818 AA.
AC A0A2M9CZ59;
DT 25-APR-2018, integrated into UniProtKB/TrEMBL.
DT 25-APR-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=RND superfamily putative drug exporter {ECO:0000313|EMBL:PJJ77209.1};
GN ORFNames=CLV28_0423 {ECO:0000313|EMBL:PJJ77209.1};
OS Sediminihabitans luteus.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Cellulomonadaceae;
OC Sediminihabitans.
OX NCBI_TaxID=1138585 {ECO:0000313|EMBL:PJJ77209.1, ECO:0000313|Proteomes:UP000231693};
RN [1] {ECO:0000313|EMBL:PJJ77209.1, ECO:0000313|Proteomes:UP000231693}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25478 {ECO:0000313|EMBL:PJJ77209.1,
RC ECO:0000313|Proteomes:UP000231693};
RA Goeker M.;
RT "Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase II
RT (KMG-II): From Individual Species to Whole Genera.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PJJ77209.1}.
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DR EMBL; PGFE01000001; PJJ77209.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2M9CZ59; -.
DR OrthoDB; 7051771at2; -.
DR Proteomes; UP000231693; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000231693};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 249..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 300..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 666..689
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 710..731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 737..755
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 273..398
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 796..818
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 818 AA; 84844 MW; 3B75813DB4235FFB CRC64;
MAELLYRLGR GSARRAWLVV VVWILALAAA GGAYAAFGGT LSSAVTIPGT PTTDVTDMLE
EEIPSTSGGT ANIVFTSADD APLTDDQQAA ISTLLGDLTD VDGVSAAIDP FSTEVDREKQ
SQDLADGQAQ LDAGRDQLTQ QQAQLDAAGV DMPEQQAQLD AAADELDAQQ AQIDQGTALL
DMASDIRTVS EDGTTVVGIL QFDKPIFEVS EDVKGEVRDE VDAAQIDGVE SYVSADLAEM
LPSLGIAEVL GVVIAAIVLF VMLGTIVAAG LPLINALVGV GVAALAALAL SGSVEMMTAT
PMLGVMIGLA VGIDYSLFIL HRHRRQLREG YTVEESIGLA TGTSGTAVVF AGMTVFIALL
ALNVTGIPFL GVMGSVAAGG VLVAVLVAIT LLPAMLGLVQ ERVLKRSERA ARAELAAAPG
PAAAAETAAD PAADRPMSTP RVVLRLVLGV AALLVIAIPS LDMRLGLPDG SSEAVDSPQY
QAYAITADKF GAGVNGPLLA VAELDEAVPA DQTTAEQVEL GQALMGLDDV VAVAPVGVSD
DGTVFAFQVV PVDGPSSVST EELVHTLRDT TVPGTDATFE VAGAASGNID ISEILSDSLP
LYLTVVIGLS LLILILVFRS ILLPVVATLG FILSLFAAFG GVTAIYQWGW LGSVFGVHDP
GPVLNFLPTI LIGVLFGLAM DYQLFIASGM REAYVHGAPA RVAVVHGVRA GRAVVTAAAI
IMISVFGGFV FSDLSMIRPI GFALAFGVLV DAFLVRMTIM PAVMHLAGDK AWWIPRWLDR
IMPDVDVEGA ALERHHPHAE ADAPAGTPEE SREATPRA
//
